The ALDH5A1 Antibody (CAB16074) is a high-quality antibody developed for reliable detection and analysis of target proteins. The antibody, raised in rabbits, exhibits strong reactivity with human samples and has been validated for use in Western blot applications. By binding to the ALDH5A1 protein, this antibody enables the detection and analysis of ALDH5A1 in a variety of cell types, making it an excellent tool for studying metabolic pathways and potentially contributing to the development of treatments for conditions related to aldehyde metabolism dysfunction.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Mouse, Rat samples.
Product Name:
ALDH5A1 Antibody
SKU:
CAB16074
Size:
20μL, 100μL
Reactivity:
Mouse, Rat
Conjugate:
Unconjugated
Immunogen:
Synthetic peptide. This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
SSDH, SSADH, ALDH5A1
Positive Sample:
Mouse liver
Cellular Localization:
Mitochondrion.
Calculated MW:
57kDa
Observed MW:
57kDa
This protein belongs to the aldehyde dehydrogenase family of proteins. This gene encodes a mitochondrial NAD(+)-dependent succinic semialdehyde dehydrogenase. A deficiency of this enzyme, known as 4-hydroxybutyricaciduria, is a rare inborn error in the metabolism of the neurotransmitter 4-aminobutyric acid (GABA). In response to the defect, physiologic fluids from patients accumulate GHB, a compound with numerous neuromodulatory properties. Two transcript variants encoding distinct isoforms have been identified for this gene.
Purification Method
Affinity purification
Gene ID
7915
RRID
AB_2763515
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of lysates from Mouse liver, using ALDH5A1 Rabbit pAb (CAB16074) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 60s.
