The ANGPTL3 Antibody (CAB0689) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, generated in rabbits, has high specificity for human samples and has been validated for use in various applications, including Western blotting. By binding to Angptl3, this antibody enables accurate detection and analysis in a range of cell types, making it a valuable resource for studies in cardiovascular disease, metabolism, and lipid biology.Angptl3 is a key player in regulating lipid levels in the blood, making it a promising target for research on conditions like hyperlipidemia, atherosclerosis, and metabolic disorders.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Mouse samples.
Product Name:
ANGPTL3 Antibody
SKU:
CAB0689
Size:
20μL, 100μL
Reactivity:
Mouse
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
ANL3, ANG-5, FHBL2, ANGPT5, ANGPTL3
Positive Sample:
Mouse liver, Mouse kidney
Cellular Localization:
Secreted.
Calculated MW:
54kDa
Observed MW:
53kDa
This gene encodes a member of a family of secreted proteins that function in angiogenesis. The encoded protein, which is expressed predominantly in the liver, is further processed into an N-terminal coiled-coil domain-containing chain and a C-terminal fibrinogen chain. The N-terminal chain is important for lipid metabolism, while the C-terminal chain may be involved in angiogenesis. Mutations in this gene cause familial hypobetalipoproteinemia type 2.
Purification Method
Affinity purification
Gene ID
27329
RRID
AB_2757340
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using ANGPTL3 Rabbit pAb (CAB0689) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST.
