The Cenexin1/ODF2 Monoclonal Antibody (CAB3607) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody is specifically raised against Cenexin1 ODF2 and is highly reactive with human samples, making it a valuable tool for immunofluorescence and immunohistochemistry applications. Cenexin1 ODF2 is essential for the formation and function of centrioles, which play a critical role in cell division and cilia assembly. Dysregulation of Cenexin1 ODF2 has been linked to various diseases, including ciliopathies and cancer.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human samples.
Product Name:
Cenexin1/ODF2 Monoclonal Antibody
SKU:
CAB3607
Size:
20μL, 100μL
Reactivity:
Human
Clone Number:
ARC2057
Conjugate:
Unconjugated
Immunogen:
Synthetic peptide. This information is considered to be commercially sensitive.
The outer dense fibers are cytoskeletal structures that surround the axoneme in the middle piece and principal piece of the sperm tail. The fibers function in maintaining the elastic structure and recoil of the sperm tail as well as in protecting the tail from shear forces during epididymal transport and ejaculation. Defects in the outer dense fibers lead to abnormal sperm morphology and infertility. This gene encodes one of the major outer dense fiber proteins. Alternative splicing results in multiple transcript variants. The longer transcripts, also known as 'Cenexins', encode proteins with a C-terminal extension that are differentially targeted to somatic centrioles and thought to be crucial for the formation of microtubule organizing centers.
Purification Method
Affinity purification
Gene ID
4957
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using Cenexin1 / ODF2 Rabbit mAb (CAB3607) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 10s.
