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Anti-HIST1H1C Antibody (CAB3299)

SKU:
CAB3299
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Synonyms:
HIST1H1C
H1.2
H1C
H1F2
H1s-1
€139 - €419
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Description

Product Name:HIST1H1C Rabbit pAb
Product Code:CAB3299
Size:100uL
Synonyms:HIST1H1C, H1.2, H1C, H1F2, H1s-1
Applications:WB
Reactivity:Human
Host Species:Rabbit
Immunogen:A synthetic peptide of human HIST1H1C
Applications:WB
Recommended Dilutions:WB 1:500 - 1:2000
Reactivity:Human
Immunogen:A synthetic peptide of human HIST1H1C
Purification Method:Affinity purification
Storage:Store at 4°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, pH7.3.
Isotype:IgG
Sequence:Email for sequence
Gene ID:3006
Uniprot:P16403
Cellular Location:Chromosome, Nucleus
Calculated MW:21kDa
Observed MW:Refer to figures
UniProt Protein Function:H1C: Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber. Histones H1 are necessary for the condensation of nucleosome chains into higher-order structured fibers. Acts also as a regulator of individual gene transcription through chromatin remodeling, nucleosome spacing and DNA methylation. Belongs to the histone H1/H5 family.
UniProt Protein Details:

Protein type:DNA-binding

Chromosomal Location of Human Ortholog: 6p21.3

Cellular Component: nucleus

Molecular Function:chromatin DNA binding; protein binding

NCBI Summary:Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H1 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6. [provided by RefSeq, Aug 2015]
UniProt Code:P16403
NCBI GenInfo Identifier:417101
NCBI Gene ID:3006
NCBI Accession:P16403.2
UniProt Secondary Accession:P16403,A8K4I2,
UniProt Related Accession:P16403
Molecular Weight:21,365 Da
NCBI Full Name:Histone H1.2
NCBI Synonym Full Names:histone cluster 1, H1c
NCBI Official Symbol:HIST1H1C  
NCBI Official Synonym Symbols:H1C; H1.2; H1F2; H1s-1  
NCBI Protein Information:histone H1.2
UniProt Protein Name:Histone H1.2
UniProt Synonym Protein Names:Histone H1c; Histone H1d; Histone H1s-1
UniProt Gene Name:HIST1H1C  
UniProt Entry Name:H12_HUMAN

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