Anti-Mouse CD200 [OX-90] In Vivo Antibody - Ultra Low Endotoxin
Introducing the Anti-Mouse CD200 [OX-90] In Vivo Antibody - Ultra Low Endotoxin from Assay Genie, a highly specific monoclonal antibody designed for in vivo applications.
This antibody targets the CD200 protein, an important regulator of immune response, making it ideal for research in immunology and related fields. With a rat IgG2a isotype, it ensures ultra-low endotoxin levels (<0.01 EU/μg), perfect for delivering consistent results in ELISA, flow cytometry, immunohistochemistry, and other assays. Available in various sizes, it is formulated in phosphate-buffered saline for maximum stability and efficacy. Enhance your research with this reliable and versatile antibody. CD200, also known as OX-2 membrane glycoprotein, is expressed on the surface of various cells including neurons, endothelial cells, and immune cells. It plays a significant role in modulating immune responses by interacting with its receptor, CD200R, on macrophages, and dendritic cells, thereby maintaining immune homeostasis and preventing autoimmune responses.
Product Name:
Anti-Mouse CD200 (Clone OX-90) In Vivo Antibody - Ultra Low Endotoxin
Product Code:
IVMB0301
Size:
1 mg, 5 mg, 25 mg, 50 mg, 100 mg
Clone:
OX-90
Protein:
CD200
Product Type:
Monoclonal Antibody
Synonyms:
OX-2
Isotype:
IgG2a
Reactivity:
Mouse
Applications:
FC, IHC, In Vivo
Formulation:
This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added.
Endotoxin Level:
<0.5 EU/mg as determined by the LAL method
Purity:
≥98% monomer by analytical SEC â‹… >95% by SDS Page
Product Preparation:
Functional grade preclinical antibodies are manufactured in an animal free facility using in vitro cell culture techniques and are purified by a multi-step process including the use of protein A or G to assure extremely low levels of endotoxins, leachable protein A or aggregates.
Applications:
FC, IHC, In Vivo
Reactivity:
Mouse
Host Species:
Rat
Specificity:
Clone OX-90 reacts with murine CD200 (OX-2).
Antigen Distribution:
Thymocytes, neurons, B cells, splenic follicular dendritic cells and endothelium, and subsets of T cells and dendritic cells
Concentration:
≥ 5.0 mg/ml
Endotoxin Level:
<0.5 EU/mg as determined by the LAL method
Formulation:
This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added.
Purity:
≥98% monomer by analytical SEC â‹… >95% by SDS Page
Preparation:
Functional grade preclinical antibodies are manufactured in an animal free facility using in vitro cell culture techniques and are purified by a multi-step process including the use of protein A or G to assure extremely low levels of endotoxins, leachable protein A or aggregates.
Storage and Handling:
Functional grade preclinical antibodies may be stored sterile as received at 2-8°C for up to one month. For longer term storage, aseptically aliquot in working volumes without diluting and store at -80°C. Avoid Repeated Freeze Thaw Cycles.
CD200 (OX-2) is an immune suppressor that regulates the of induction of cytokine production by conventional allostimulatory DC1,2. CD200 limits pro-inflammatory signals and has been shown to play an important role in cancer and immune disorders3,4.
Protein:
CD200
Research Area:
Immunology
Pathogen Testing:
To protect mouse colonies from infection by pathogens and to assure that experimental preclinical data is not affected by such pathogens, all of Assay Genie's Purified Functional Antibodies are tested and guaranteed to be negative for all pathogens in the IDEXX IMPACT I Mouse Profile.
