The Anti-SCAF8 Antibody (CAB19467) is a valuable tool for researchers studying SCAF8, a protein involved in mRNA splicing and gene expression regulation. This polyclonal antibody, produced in rabbits, exhibits high reactivity with human samples and is suitable for use in Western blot applications. By binding specifically to the SCAF8 protein, it enables detection and analysis in various cell types, making it ideal for research in molecular biology and genetics.SCAF8, also known as SR-related CTD-associated factor 8, plays a crucial role in splicing regulation and RNA processing, influencing gene expression patterns and cellular functions.
Its involvement in these processes makes it a key target for investigation in studies on gene regulation, RNA biology, and developmental biology. Understanding the function of SCAF8 can provide insights into mechanisms underlying genetic disorders, cancer development, and other diseases with aberrant gene expression patterns. Overall, the Anti-SCAF8 Antibody (CAB19467) offers researchers a reliable tool for exploring the role of SCAF8 in cellular processes and disease development, contributing to advancements in molecular biology and gene regulation research.
Product Name:
SCAF8 Rabbit Polyclonal Antibody
SKU:
CAB19467
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 572-634 of human SCAF8 (NP_055707.3).
Enables RNA binding activity and RNA polymerase II C-terminal domain phosphoserine binding activity. Involved in negative regulation of termination of RNA polymerase II transcription, poly(A)-coupled and positive regulation of DNA-templated transcription, elongation. Located in nucleoplasm.
Purification Method:
Affinity purification
Gene ID:
22828
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using SCAF8 antibody (CAB19467) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
