[KO Validated] Substance P Polyclonal Antibody (CAB20772)
The Anti-Substance P Antibody (CAB20772) is a high-quality research tool designed for the detection and analysis of Substance P, a neuropeptide involved in pain transmission and inflammation. This antibody, produced through knockout validated techniques, is highly specific to Substance P and has been validated for use in various applications, including Western blotting and immunohistochemistry.Substance P is known for its role in mediating pain and inflammatory responses in the body, making it a key target for studying conditions such as chronic pain, neuroinflammation, and autoimmune diseases. By using the Anti-Substance P Antibody, researchers can effectively detect and measure levels of Substance P in biological samples, providing valuable insights into the mechanisms underlying these conditions.
With its high specificity and sensitivity, the Anti-Substance P Antibody is an essential tool for researchers working in the fields of neuroscience, pain management, and immune response modulation. Its knockout validation ensures reliable and reproducible results, making it a trusted choice for studies aiming to elucidate the role of Substance P in various physiological and pathological processes.
Product Name:
[KO Validated] Substance P Polyclonal Antibody
SKU:
CAB20772
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Substance P (NP_003173.1).
This gene encodes four products of the tachykinin peptide hormone family, substance P and neurokinin A, as well as the related peptides, neuropeptide K and neuropeptide gamma. These hormones are thought to function as neurotransmitters which interact with nerve receptors and smooth muscle cells. They are known to induce behavioral responses and function as vasodilators and secretagogues. Substance P is an antimicrobial peptide with antibacterial and antifungal properties. Multiple transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
6863
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Immunofluorescence analysis of SH-SY5Y cells using [KO Validated] Substance P Rabbit pAb (CAB20772) at dilution of 1:300 (40x lens). Secondary antibody: Cy3 Goat Anti-Rabbit IgG (H+L) (CABS007) at 1:500 dilution. Blue: DAPI for nuclear staining.