The Tyrosine Hydroxylase Monoclonal Antibody (CAB0730) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, raised in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. It is designed to detect and analyze the Tyro3 protein in various cell types, making it an invaluable tool for studies in immunology and cancer research.Tyro3 is known for its role in regulating immune responses and controlling inflammation. It is also implicated in the development and progression of various cancers, making it a promising target for research into cancer therapies.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
Tyrosine Hydroxylase Monoclonal Antibody
SKU:
CAB0730
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Clone Number:
ARC1841
Conjugate:
Unconjugated
Immunogen:
Synthetic peptide. This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
BYK, Dtk, RSE, Rek, Sky, Tif, Etk-2, Tyro3
Positive Sample:
C6, SH-SY5Y, Mouse testis, Mouse brain
Cellular Localization:
Cell Membrane.
Calculated MW:
97kDa
Observed MW:
130kDa
The gene is part of a 3-member transmembrane receptor kinase receptor family with a processed pseudogene distal on chromosome 15. The encoded protein is activated by the products of the growth arrest-specific gene 6 and protein S genes and is involved in controlling cell survival and proliferation, spermatogenesis, immunoregulation and phagocytosis. The encoded protein has also been identified as a cell entry factor for Ebola and Marburg viruses.
Purification Method
Affinity purification
Gene ID
7301
RRID
AB_2861478
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using Tyro3 Rabbit mAb (CAB0730) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 30s.
