The VWF Monoclonal Antibody (CAB13523) is a high-quality antibody developed for reliable detection and analysis of target proteins. This polyclonal antibody, raised in rabbits, exhibits high reactivity with human samples and has been validated for use in applications such as Western blotting.vWF is essential for platelet adhesion and aggregation at sites of vascular injury, making it a crucial component of the coagulation cascade. Dysregulation of vWF has been implicated in various bleeding disorders and thrombotic conditions, highlighting the importance of studying its function in both health and disease contexts.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Mouse samples.
Product Name:
VWF Monoclonal Antibody
SKU:
CAB13523
Size:
20μL, 100μL
Reactivity:
Mouse
Clone Number:
ARC0716
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
This gene encodes a glycoprotein involved in hemostasis. The encoded preproprotein is proteolytically processed following assembly into large multimeric complexes. These complexes function in the adhesion of platelets to sites of vascular injury and the transport of various proteins in the blood. Mutations in this gene result in von Willebrand disease, an inherited bleeding disorder. An unprocessed pseudogene has been found on chromosome 22.
Purification Method
Affinity purification
Gene ID
7450
RRID
AB_2861690
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of lysates from Mouse liver, using von Willebrand factor (VWF) Rabbit mAb (CAB13523) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 3min.
