The ARF6 Monoclonal Antibody (CAB11485) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, derived from rabbit cells, is highly specific and reactive with human samples, making it suitable for a range of applications including Western blot, immunofluorescence, and immunohistochemistry.ARF6 is a small GTPase protein that plays a crucial role in cellular processes such as endocytosis, exocytosis, and cell migration. Dysregulation of ARF6 has been implicated in various diseases including cancer, neurodegenerative disorders, and infectious diseases.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
ARF6 Monoclonal Antibody
SKU:
CAB11485
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Clone Number:
ARC0617
Conjugate:
Unconjugated
Immunogen:
Synthetic peptide. This information is considered to be commercially sensitive.
This gene encodes a member of the human ARF gene family, which is part of the RAS superfamily. The ARF genes encode small guanine nucleotide-binding proteins that stimulate the ADP-ribosyltransferase activity of cholera toxin and play a role in vesicular trafficking and as activators of phospholipase D. The product of this gene is localized to the plasma membrane, and regulates vesicular trafficking, remodelling of membrane lipids, and signaling pathways that lead to actin remodeling. A pseudogene of this gene is located on chromosome 7.
Purification Method
Affinity purification
Gene ID
382
RRID
AB_2861580
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using ARF6 Rabbit mAb (CAB11485) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 3min.
Western blot analysis of various lysates using ARF6 Rabbit mAb (CAB11485) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (AbGn00021). Exposure time: 3min.
