Biotinylated Recombinant Human TGF-beta receptor type-1/TGFR-1/ALK-5 Protein
The Biotinylated Recombinant Human TGF-beta receptor type-1/TGFR-1/ALK-5 Protein is a biologically active recombinant protein that plays a significant role in various cellular processes and signaling pathways in human biology. This protein is widely employed in immunological research, cell biology studies, protein-protein interaction analyses, and therapeutic development, providing researchers with a reliable tool for investigating Biotinylated TGF-beta receptor type-1/TGFR-1/ALK-5 function and its implications in health and disease.
This product (SKU: RPCB0083) is produced using advanced expression systems and features a C-mFc&Avi tag for convenient detection and purification. The protein exhibits a calculated molecular weight of 38.2 kDa with an observed molecular weight of 50-55 kDa under denaturing conditions, achieving ≥ 95 % as determined by Tris-Bis PAGE., ensuring exceptional quality and consistency for research applications.
Key Features
High Purity by Affinity Chromatography
Mammalian & Bacterial Expression Systems
High lot-to-lot consistency via strict QC
Product Name:
Biotinylated Recombinant Human TGF-beta receptor type-1/TGFR-1/ALK-5 Protein
High quality, high purity and low endotoxin recombinant Biotinylated Recombinant Human TGF-beta receptor type-1/TGFR-1/ALK-5 Protein (RPCB0083), tested reactivity in HEK293 cells and has been validated in SDS-PAGE.100% guaranteed.
Endotoxin:
< 1 EU/μg of the protein by LAL method.
Purity:
≥ 95 % as determined by Tris-Bis PAGE.
Formulation:
Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
Reconstitution:
Centrifuge the tube before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
Storage:
Store at -20℃. Store the lyophilized protein at -20℃ to -80℃ up to 1 year from the date of receipt. After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.
transforming growth factor beta receptor 1 (TGFBR1), a key stimulator of tumor proliferation and metastasis, was a direct target of miR?98?5p. miR?98?5p overexpression resulted in the downregulation of TGFBR1 and the suppression of the viability, proliferation, migration and invasion of A549 and H1299 cells.
Biotinylated Recombinant Human TGF-beta receptor type-1/TGFR-1/ALK-5 Protein was determined by Tris-Bis PAGE under reducing conditions.
