Description
Biotinylated Recombinant Human Tyrosine-protein kinase receptor UFO/Axl Protein
The Biotinylated Recombinant Human Tyrosine-protein kinase receptor UFO/Axl Protein is a biologically active recombinant protein that plays a significant role in various cellular processes and signaling pathways in human biology. This protein is widely employed in immunological research, cell biology studies, protein-protein interaction analyses, and therapeutic development, providing researchers with a reliable tool for investigating Biotinylated Tyrosine-protein kinase receptor UFO/Axl function and its implications in health and disease.
This product (SKU: RPCB0048) is produced using advanced expression systems and features a C-His&Avi tag for convenient detection and purification. The protein exhibits a calculated molecular weight of 48.7 kDa with an observed molecular weight of 70-80 kDa under denaturing conditions, achieving ≥ 95 % as determined by Tris-Bis PAGE;≥ 95 % as determined by HPLC., ensuring exceptional quality and consistency for research applications.
Key Features
| High Purity by Affinity Chromatography | |
| Mammalian & Bacterial Expression Systems | |
| High lot-to-lot consistency via strict QC |
| Product Name: | Biotinylated Recombinant Human Tyrosine-protein kinase receptor UFO/Axl Protein |
| SKU: | RPCB0048 |
| Size: | 100 μg |
| Reactivity: | Human |
| Synonyms: | AXL, ARK, JTK11, Tyro7, UFO |
| Tag: | C-His&Avi |
| Calculated MW: | 48.7 kDa |
| Observed MW: | 70-80 kDa |
| Gene ID: | 558 |
| Protein Description: | High quality, high purity and low endotoxin recombinant Biotinylated Recombinant Human Tyrosine-protein kinase receptor UFO/Axl Protein (RPCB0048), tested reactivity in HEK293 cells and has been validated in SDS-PAGE.100% guaranteed. |
| Endotoxin: | < 1 EU/μg of the protein by LAL method. |
| Purity: | ≥ 95 % as determined by Tris-Bis PAGE;≥ 95 % as determined by HPLC. |
| Formulation: | Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4. |
| Reconstitution: | Centrifuge the tube before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles. |
| Storage: | Store at -20℃. Store the lyophilized protein at -20℃ to -80℃ up to 1 year from the date of receipt. After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week. |
Axl, a member of the TAM (Tyro3, Axl, Mer) family, and its inhibitors can specifically break the kinase signaling nodes, allowing advanced patients to regain drug sensitivity with improved therapeutic efficacy. Overexpression and activation of Axl receptor tyrosine kinase have been widely accepted to promote cell proliferation, chemotherapy resistance, invasion, and metastasis in several human cancers, such as lung, breast, and pancreatic cancers.
 | Biotinylated Recombinant Human Tyrosine-protein kinase receptor UFO/Axl Protein was determined by Tris-Bis PAGE under reducing conditions. |
 | The purity of Biotinylated Human AXL is greater than 95% as determined by SEC-HPLC. |
