The Calcoco1 Polyclonal Antibody (CAB7987) is a valuable tool for researchers studying the Calcoco1 protein, a key player in autophagy regulation and tumor suppression mechanisms. This antibody, developed from rabbits, demonstrates high reactivity with human samples and is validated for use in Western blotting applications. By binding specifically to the Calcoco1 protein, this antibody enables precise detection and analysis in a variety of cell types, making it a valuable asset in studies related to autophagy, cancer biology, and tumor suppressor mechanisms.
Calcoco1, also known as BNIP3L, is a critical regulator of autophagy, a process vital for maintaining cellular homeostasis and preventing tumorigenesis. Its role in promoting autophagic responses to cellular stresses highlights its potential as a therapeutic target for cancer treatment and other diseases related to cellular dysfunction. Research into the function and regulation of Calcoco1 is essential for developing targeted therapies that can harness the autophagic machinery for therapeutic purposes in cancer and other diseases.
Product Name:
CALCOCO1 Rabbit Polyclonal Antibody
SKU:
CAB7987
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 462-691 of human CALCOCO1 (NP_065949.1).
Enables several functions, including armadillo repeat domain binding activity; beta-catenin binding activity; and nuclear receptor coactivator activity. Involved in positive regulation of gene expression and positive regulation of transcription, DNA-templated. Located in cytosol and nucleus.
Purification Method:
Affinity purification
Gene ID:
57658
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using CALCOCO1 antibody (CAB7987) at 1:1000 dilution._Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution._Lysates/proteins: 25μg per lane._Blocking buffer: 3% nonfat dry milk in TBST._Detection: ECL Enhanced Kit (AbGn00021)._Exposure time: 90s.
