The Cathepsin G Monoclonal Antibody (CAB22047) is a specialized tool for researchers investigating the role of Cathepsin G, a serine protease enzyme involved in immune responses and inflammatory processes. This monoclonal antibody, generated in mice, exhibits high specificity and sensitivity in detecting Cathepsin G in human samples, making it an essential component in studies related to immunology, inflammation, and cancer.Cathepsin G is known for its ability to modulate the immune system by regulating the activity of cytokines, chemokines, and other immune mediators. Dysregulation of Cathepsin G has been linked to various diseases, including inflammatory conditions, autoimmune disorders, and cancer progression.
By targeting Cathepsin G with this monoclonal antibody, researchers can gain valuable insights into its function and potential therapeutic applications.With its validated performance in techniques like Western blotting, the Cathepsin G Monoclonal Antibody (CAB22047) enables precise detection and quantification of Cathepsin G in different cell types and tissues. By utilizing this antibody in their experiments, scientists can advance their understanding of Cathepsin G biology and its implications in disease pathology, ultimately paving the way for innovative treatment strategies and drug development.
Product Name:
Cathepsin G Monoclonal Antibody
SKU:
CAB22047
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 156-255 of human Cathepsin G (NP_001902.1).
The protein encoded by this gene, a member of the peptidase S1 protein family, is found in azurophil granules of neutrophilic polymorphonuclear leukocytes. The encoded protease has a specificity similar to that of chymotrypsin C, and may participate in the killing and digestion of engulfed pathogens, and in connective tissue remodeling at sites of inflammation. In addition, the encoded protein is antimicrobial, with bacteriocidal activity against S. aureus and N. gonorrhoeae. Transcript variants utilizing alternative polyadenylation signals exist for this gene.
Purification Method:
Affinity purification
Gene ID:
1511
Clone Number:
ARC54789
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Confocal imaging of THP-1 cells using Cathepsin G Rabbit mAb (A22047,dilution 1:200) followed by a further incubation with Cy3 Goat Anti-Rabbit IgG (H+L) (AS007,dilution 1:500)(Red).DAPI was used for nuclear staining (Blue). Objective: 100x.
