The CEP164 Polyclonal Antibody (CAB9964) is a valuable tool for researchers studying CEP164, a protein involved in centrosome biogenesis and ciliogenesis. This antibody, raised in rabbits, is highly specific for detecting CEP164 in human samples and is validated for use in Western blot applications. By targeting the CEP164 protein, this antibody allows for precise detection and analysis of CEP164 expression in various cell types, making it ideal for research in cell biology and cilia-related disorders.
CEP164 is a key player in centrosome duplication and ciliogenesis, processes critical for cell division and signaling. Dysregulation of CEP164 has been implicated in a variety of ciliopathies, including Bardet-Biedl syndrome and Meckel-Gruber syndrome. Investigating the function and regulation of CEP164 is essential for understanding the molecular mechanisms underlying these disorders and developing potential therapeutic strategies to target cilia-related diseases.
Product Name:
CEP164 Rabbit Polyclonal Antibody
SKU:
CAB9964
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 730-829 of human CEP164 (NP_055771.4).
This gene encodes a centrosomal protein involved in microtubule organization, DNA damage response, and chromosome segregation. The encoded protein is required for assembly of primary cilia and localizes to mature centrioles. Defects in this gene are a cause of nephronophthisis-related ciliopathies. Two transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
22897
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of lysates from A-375 cells, using CEP164 Rabbit pAb (CAB9964) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
