The CLNS1A Antibody (CAB9739) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, has high reactivity with human samples and is validated for use in Western blot applications. By binding specifically to CLNS1A, researchers can accurately detect and analyze this protein in various cell types, making it an essential component for studies in neuroscience and neurodegenerative diseases.CLNS1A, also known as Battenin, is essential for normal cellular function in the brain and nervous system. Mutations in the CLNS1A gene have been linked to Batten disease, a rare and fatal neurodegenerative disorder that affects children.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human samples.
Product Name:
CLNS1A Antibody
SKU:
CAB9739
Size:
20μL, 100μL
Reactivity:
Human
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
CLCI, ICln, CLNS1B, CLNS1A
Positive Sample:
293T, DU145, Jurkat, HeLa
Cellular Localization:
Cytoplasm, Nucleus, Cytoskeleton, Cytosol.
Calculated MW:
26kDa
Observed MW:
38kDa
This gene encodes a protein that functions in multiple regulatory pathways. The encoded protein complexes with numerous cytosolic proteins and performs diverse functions including regulation of small nuclear ribonucleoprotein biosynthesis, platelet activation and cytoskeletal organization. The protein is also found associated with the plasma membrane where it functions as a chloride current regulator. Pseudogenes of this gene are found on chromosomes 1, 4 and 6. Several transcript variants encoding different isoforms have been found for this gene.
Purification Method
Affinity purification
Gene ID
1207
RRID
AB_2768956
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using CLNS1A Rabbit pAb (CAB9739) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (AbGn00021). Exposure time: 90s.
