The CLSPN Antibody (CAB17202) is a high-quality antibody developed for reliable detection and analysis of target proteins. This rabbit-derived antibody is highly specific for binding to human samples and has been validated for use in Western blot applications. By targeting the CLSPN protein, this antibody allows for the detection and analysis of CLSPN in various cell types, making it an ideal choice for studies in molecular biology and cancer research.CLSPN, also known as the Claspin protein, plays a crucial role in coordinating the cellular response to DNA damage, particularly in the activation of the checkpoint kinase pathway.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human samples.
Product Name:
CLSPN Antibody
SKU:
CAB17202
Size:
20μL, 100μL
Reactivity:
Human
Immunogen:
Synthetic peptide. This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
CLSPN, claspin
Positive Sample:
HepG2, Jurkat
Cellular Localization:
Golgi Apparatus, Nucleoplasm, Nucleus.
Calculated MW:
151kDa
Observed MW:
275kDa
The product of this gene is an essential upstream regulator of checkpoint kinase 1 and triggers a checkpoint arrest of the cell cycle in response to replicative stress or DNA damage. The protein is also required for efficient DNA replication during a normal S phase. Multiple transcript variants encoding different isoforms have been found for this gene.
Purification Method
Affinity purification
Gene ID
63967
RRID
AB_2768961
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using CLSPN Rabbit pAb (CAB17202) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (AbGn00021). Exposure time: 150s.
