The COP1 Polyclonal Antibody (CAB22106) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, generated in rabbits, exhibits high specificity and sensitivity for detecting COP1 in human samples. Validated for use in Western blotting, it allows for the precise identification and analysis of COP1 expression in various cell types.COP1, known for its role in controlling cell proliferation and apoptosis, is a crucial factor in cancer development and progression.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human samples.
Product Name:
COP1 Polyclonal Antibody
SKU:
CAB22106
Size:
20μL, 100μL
Reactivity:
Human
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
FAP78, RFWD2, CFAP78, RNF200, COP1
Positive Sample:
293T
Cellular Localization:
Cytoplasm, Nucleus Speckle.
Calculated MW:
80kDa
Observed MW:
102kDa
Enables ubiquitin protein ligase activity. Involved in positive regulation of proteasomal ubiquitin-dependent protein catabolic process; proteasome-mediated ubiquitin-dependent protein catabolic process; and response to ionizing radiation. Part of Cul4A-RING E3 ubiquitin ligase complex.
Purification Method
Affinity purification
Gene ID
64326
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of lysates from 293T cells, using COP1 Rabbit pAb (CAB22106) at 1:600 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 90s.
