Description
CSNK1A1L/CSNK1A1 Antibody (PACO23264)
The CSNK1A1L/CSNK1A1 Antibody (PACO23264) is a highly specific tool for researchers studying CSNK1A1L and CSNK1A1, protein kinases involved in various signaling pathways and cellular processes. This polyclonal antibody is produced in rabbits and demonstrates strong reactivity with human samples, making it reliable for use in Western blot applications.CSNK1A1L and CSNK1A1 are known to play key roles in regulating cell growth, proliferation, and differentiation, as well as in modulating circadian rhythms and DNA damage response. By targeting these proteins with the PACO23264 antibody, researchers can gain valuable insights into the mechanisms underlying these processes and their implications in diseases such as cancer, neurodegenerative disorders, and metabolic disorders.
This antibody provides a powerful tool for investigating the functions of CSNK1A1L and CSNK1A1 in various cell types and tissues, enabling researchers to uncover new therapeutic targets and develop innovative approaches for treating diseases associated with dysregulation of these protein kinases. Its high specificity and reactivity make it a reliable asset for studies in molecular biology, cell biology, and biomedical research.
| Antibody Name: | CSNK1A1L/CSNK1A1 Antibody (PACO23264) |
| Antibody SKU: | PACO23264 |
| Size: | 100ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:50-1:100, IF:1:100-1:500 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Synthesized peptide derived from internal of human CKI- alpha 1/L. |
| Form: | Liquid |
| Storage Buffer: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemistry analysis of paraffin-embedded human testis tissue, using CKI-alpha 1/L antibody. |
 | Immunofluorescence analysis of A549 cells, using CKI- alpha 1/L antibody. |
| Background: | Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling By similarity. |
| Synonyms: | CK1; CK1-alpha2; CKI-alpha; CSNK1A1L; EC 2.7.11.1 |
| UniProt Protein Function: | CK1A2: Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily. |
| UniProt Protein Details: | Protein type:Kinase, protein; Protein kinase, Ser/Thr (non-receptor); EC 2.7.11.1; Protein kinase, CK1; CK1 group; CK1 family Chromosomal Location of Human Ortholog: 13q13.3 Cellular Component: cytoplasm; nucleus; ribonucleoprotein complex Molecular Function:protein serine/threonine kinase activity; ATP binding Biological Process: regulation of cell shape; peptidyl-serine phosphorylation; Wnt receptor signaling pathway; cell morphogenesis; phagocytosis |
| UniProt Code: | Q8N752 |
| NCBI GenInfo Identifier: | 212286065 |
| NCBI Gene ID: | 122011 |
| NCBI Accession: | Q8N752.2 |
| UniProt Secondary Accession: | Q8N752,Q5T2N2, |
| UniProt Related Accession: | Q8N752 |
| Molecular Weight: | 337 |
| NCBI Full Name: | Casein kinase I isoform alpha-like |
| NCBI Synonym Full Names: | casein kinase 1, alpha 1-like |
| NCBI Official Symbol: | CSNK1A1LÂ Â |
| NCBI Official Synonym Symbols: | CK1Â Â |
| NCBI Protein Information: | casein kinase I isoform alpha-like; CKI-alpha-like; casein kinase I alpha S-like |
| UniProt Protein Name: | Casein kinase I isoform alpha-like |
| UniProt Synonym Protein Names: | CK1 |
| Protein Family: | Casein kinase |
| UniProt Gene Name: | CSNK1A1LÂ Â |
| UniProt Entry Name: | KC1AL_HUMAN |
