The CTBP1 Polyclonal Antibody (CAB16825) is a valuable tool for researchers studying CTBP1, a transcriptional corepressor involved in various cellular processes, including gene regulation and cell proliferation. This antibody, produced in rabbits, exhibits high specificity and sensitivity when detecting CTBP1 in human samples, making it suitable for Western blot applications.CTBP1, also known as C-terminal binding protein 1, plays a critical role in controlling gene expression and cellular pathways related to development, metabolism, and tumorigenesis.
Understanding the functions and mechanisms of CTBP1 is essential for unraveling its contributions to disease development, particularly in cancer biology and metabolic disorders. The CTBP1 Polyclonal Antibody facilitates the detection and analysis of CTBP1 levels in different cell types, offering researchers a valuable tool for advancing their understanding of this important regulatory protein.
Product Name:
CtBP1 Rabbit Polyclonal Antibody
SKU:
CAB16825
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 20-250 of human CtBP1 (NP_001319.1).
This gene encodes a protein that binds to the C-terminus of adenovirus E1A proteins. This phosphoprotein is a transcriptional repressor and may play a role during cellular proliferation. This protein and the product of a second closely related gene, CTBP2, can dimerize. Both proteins can also interact with a polycomb group protein complex which participates in regulation of gene expression during development. Alternative splicing of transcripts from this gene results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
1487
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from Rat brain, using CtBP1 Rabbit pAb (CAB16825) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
