The CTP synthase/CTPS Monoclonal Antibody (CAB20912) is a high-quality antibody developed for reliable detection and analysis of target proteins. This polyclonal antibody, generated in rabbits, is highly specific to human CTPS and has been validated for use in Western blot applications. By targeting the CTPS protein, this antibody allows for the accurate detection and analysis of CTPS expression in various cell types.CTPS plays a crucial role in the production of CTP, a critical building block for DNA and RNA synthesis. Dysregulation of CTPS has been implicated in various diseases, including cancer and autoimmune disorders, making it an attractive target for therapeutic intervention.
This antibody is validated for use in WB, IP, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
CTP synthase/CTPS Monoclonal Antibody
SKU:
CAB20912
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Clone Number:
ARC2883
Conjugate:
Unconjugated
Immunogen:
Synthetic peptide. This information is considered to be commercially sensitive.
0.5μg-4μg antibody for 200μg-400μg extracts of whole cells
ELISA
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
CTPS, GATD5, IMD24, GATD5A, CTP synthase / CTPS
Positive Sample:
HeLa, A-549, Mouse lung, Rat lung, Rat brain, HeLa
Cellular Localization:
Cytoplasm, Cytosol.
Calculated MW:
67kDa
Observed MW:
78KDa
This gene encodes an enzyme responsible for the catalytic conversion of UTP (uridine triphosphate) to CTP (cytidine triphospate). This reaction is an important step in the biosynthesis of phospholipids and nucleic acids. Activity of this proten is important in the immune system, and loss of function of this gene has been associated with immunodeficiency. Alternative splicing results in multiple transcript variants.
Purification Method
Affinity purification
Gene ID
1503
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using CTP synthase / CTPS Rabbit mAb (CAB20912) at 1:500 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 10s.
Western blot analysis of various lysates using CTP synthase / CTPS Rabbit mAb (CAB20912) at 1:500 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 90s.
