The CTPS1 Antibody (CAB3817) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, shows high reactivity with human samples and is suitable for use in Western blot applications. By binding specifically to the CTPS1 protein, this antibody enables precise detection and analysis in various cell types, making it an ideal choice for studies in molecular biology and cancer research.CTPS1, also known as CTP synthase 1, is a key enzyme in the de novo synthesis of CTP, a crucial building block for DNA and RNA. Dysregulation of CTPS1 has been implicated in various diseases, including cancer, autoimmune disorders, and metabolic disorders.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse samples.
Product Name:
CTPS1 Antibody
SKU:
CAB3817
Size:
20μL, 100μL
Reactivity:
Human, Mouse
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
CTPS, GATD5, IMD24, GATD5A, CTPS1
Positive Sample:
Raji, HeLa, 22Rv1, Jurkat, Mouse brain
Cellular Localization:
Cytoplasm, Cytosol.
Calculated MW:
67kDa
Observed MW:
80kDa
This gene encodes an enzyme responsible for the catalytic conversion of UTP (uridine triphosphate) to CTP (cytidine triphospate). This reaction is an important step in the biosynthesis of phospholipids and nucleic acids. Activity of this proten is important in the immune system, and loss of function of this gene has been associated with immunodeficiency. Alternative splicing results in multiple transcript variants.
Purification Method
Affinity purification
Gene ID
1503
RRID
AB_2765320
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using CTPS1 Rabbit pAb (CAB3817) at 1:3000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 5s.
