The DCP1A Antibody (CAB7376) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, generated in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By binding specifically to DCP1A protein, this antibody enables accurate detection and analysis in a variety of cell types, making it ideal for investigations in molecular biology and RNA metabolism.DCP1A is a critical component of the mRNA degradation pathway, playing a crucial role in post-transcriptional gene regulation. Its involvement in mRNA processing has implications for the control of gene expression and cellular responses to environmental stimuli.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
DCP1A Antibody
SKU:
CAB7376
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
SMIF, SMAD4IP1, HSA275986, Nbla00360, DCP1A
Positive Sample:
HepG2, Jurkat, Mouse brain, Rat brain
Cellular Localization:
Cytoplasm, Nucleus, P-Body.
Calculated MW:
63kDa
Observed MW:
70kDa
Decapping is a key step in general and regulated mRNA decay. The protein encoded by this gene is a decapping enzyme. This protein and another decapping enzyme form a decapping complex, which interacts with the nonsense-mediated decay factor hUpf1 and may be recruited to mRNAs containing premature termination codons. This protein also participates in the TGF-beta signaling pathway. Alternative splicing of this gene results in multiple transcript variants.
Purification Method
Affinity purification
Gene ID
55802
RRID
AB_2767909
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.09% Sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using DCP1A Rabbit pAb (CAB7376) at 1:500 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 30s.
