The eNOS Polyclonal Antibody is a crucial tool for researchers studying endothelial nitric oxide synthase (eNOS), an enzyme involved in the production of nitric oxide and regulation of vascular tone. This antibody, generated in rabbits, is highly specific to human samples and is validated for use in Western blot applications. By binding to the eNOS protein, this antibody facilitates the detection and analysis of eNOS expression in various cell types, making it an essential tool for studies in cardiovascular biology and related fields.eNOS plays a vital role in the cardiovascular system by regulating blood pressure, vascular tone, and angiogenesis.
Dysregulation of eNOS activity is associated with various cardiovascular diseases, including hypertension, atherosclerosis, and heart failure. Therefore, understanding the function and regulation of eNOS is essential for developing novel therapeutic strategies for cardiovascular disorders.Overall, the eNOS Polyclonal Antibody serves as a valuable resource for researchers investigating the role of eNOS in cardiovascular health and disease. Its high specificity and sensitivity make it an ideal choice for studies aiming to elucidate the molecular mechanisms underlying cardiovascular physiology and pathology.
Product Name:
eNOS Polyclonal Antibody
SKU:
CAB21751
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1035-1110 of human eNOS (NP_000594.2).
Nitric oxide is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral activities. Nitric oxide is synthesized from L-arginine by nitric oxide synthases. Variations in this gene are associated with susceptibility to coronary spasm. Alternative splicing and the use of alternative promoters results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
4846
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Immunofluorescence analysis of human placenta cells using eNOS Rabbit pAb (CAB21751) at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.
