The ESRRA Antibody (CAB1798) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, generated in rabbits, displays high specificity and sensitivity towards human samples and has been validated for use in various applications, including Western blotting.ESRRA is a key regulator of genes involved in oxidative metabolism and plays a crucial role in the maintenance of cellular energy balance. Dysregulation of ESRRA has been linked to a variety of metabolic disorders, making it an attractive target for further investigation in research areas such as metabolic diseases, cancer, and aging.
This antibody is validated for use in WB, IF/ICC, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
ESRRA Antibody
SKU:
CAB1798
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
ERR1, ERRa, ESRL1, NR3B1, ERRalpha, ESRRA
Positive Sample:
SW620, HT-29, BT-474, MCF7
Cellular Localization:
Nucleus.
Calculated MW:
46kDa
Observed MW:
53kDa
The protein encoded by this gene is a nuclear receptor that is most closely related to the estrogen receptor. This protein acts as a site-specific transcription factor and interacts with members of the PGC-1 family of transcription cofactors to regulate the expression of most genes involved in cellular energy production as well as in the process of mitochondrial biogenesis. A processed pseudogene of ESRRA is located on chromosome 13q12.1.
Purification Method
Affinity purification
Gene ID
2101
RRID
AB_2763837
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.09% Sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using ESRRA Rabbit pAb (CAB1798) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST.
