The FBP1 Monoclonal Antibody (CAB11664) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced using advanced monoclonal technology, exhibits high specificity and sensitivity in detecting FBP1 in various cell types and tissues.FBP1, also known as fructose-1,6-bisphosphatase 1, is a key enzyme involved in gluconeogenesis, the process of generating glucose from non-carbohydrate sources. Dysregulation of FBP1 has been implicated in various types of cancer, making it an attractive target for therapeutic interventions.
This antibody is validated for use in WB, IF/ICC, ELISA, IF-P applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
FBP1 Monoclonal Antibody
SKU:
CAB11664
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Clone Number:
ARC0664
Conjugate:
Unconjugated
Immunogen:
Synthetic peptide. This information is considered to be commercially sensitive.
Fructose-1,6-bisphosphatase 1, a gluconeogenesis regulatory enzyme, catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate and inorganic phosphate. Fructose-1,6-diphosphatase deficiency is associated with hypoglycemia and metabolic acidosis.
Purification Method
Affinity purification
Gene ID
2203
RRID
AB_2861622
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using FBP1 Rabbit mAb (CAB11664) at 1:3000 dilution incubated overnight at 4℃. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25 μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 3 s.
Immunofluorescence analysis of HeLa cells using FBP1 Rabbit mAb (CAB11664) at dilution of 1:100 (40x lens). Secondary antibody: Cy3-conjugated Goat anti-Rabbit IgG (H+L) (CABS007) at 1:500 dilution. Blue: DAPI for nuclear staining.
Immunofluorescence analysis of paraffin-embedded mouse kidney using FBP1 Rabbit mAb (CAB11664) at dilution of 1:100 (40x lens). Secondary antibody: Cy3-conjugated Goat anti-Rabbit IgG (H+L) (CABS007) at 1:500 dilution. Blue: DAPI for nuclear staining.
