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FITC Anti-Human CD185/CXCR5 Antibody [J252D4] (AGEL3394)

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SKU AGEL3394
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FCM
Reactivity Human
Host Species Mouse
Isotype Mouse IgG1, k
Clone J252D4
Conjugation FITC
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Description

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FITC Anti-Human CD185/CXCR5 Antibody [J252D4]

The FITC Anti-Human CD185 (CXCR5) Antibody (J252D4) is a specialized tool for researchers studying the CXCR5 protein, a vital cell surface receptor involved in immune response regulation. This antibody is conjugated with fluorescein isothiocyanate (FITC), enabling easy visualization and analysis of CXCR5 expression in human samples.CXCR5, a chemokine receptor, plays a pivotal role in guiding immune cells to specific locations within the body, particularly in lymphoid tissues. By targeting CXCR5, researchers can investigate its involvement in immune cell migration, homing, and function. The FITC Anti-Human CD185 (CXCR5) Antibody (J252D4) is highly specific and reliable for techniques such as flow cytometry and immunofluorescence, providing valuable insights into the role of CXCR5 in various immunological processes.

Understanding the mechanisms of CXCR5 signaling is essential for deciphering key immune responses and cell trafficking patterns, with implications for diseases ranging from infections to autoimmune disorders. By utilizing this antibody, researchers can delve deeper into the complexities of immune system regulation, paving the way for innovative therapeutic interventions and targeted treatment strategies.

Product Title:FITC Anti-Human CD185/CXCR5 Antibody [J252D4]
SKU:AGEL3394
Size:20 Tests, 100 Tests, 200 Tests
Clone No:J252D4
Synonyms:CXCR5;C-X-C chemokine receptor type 5;Burkitt lymphoma receptor 1;BLR1;Monocyte-derived receptor 15;MDR15;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:FITC Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:FITC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P32302
Gene ID:643
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD185, also known as CXCR5, is a 42 kD G-protein coupled receptor with seven transmembrane regions. CXCR5 is expressed by mature B cells, follicular helper T cells, Burkitt’s lymphoma cells and a subset of neurons, and mediates cell migration to the B cell follicles in the secondary lymphoid organs. The ligand of CXCR5 is CXCL13 (BLC).

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