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FITC Anti-Human CD20 Antibody [BCA/B20] (AGEL2812)

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SKU AGEL2812
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FCM
Reactivity Human
Host Species Mouse
Isotype Mouse IgG2a, κ
Clone BCA/B20
Conjugation FITC
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Description

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FITC Anti-Human CD20 Antibody [BCA/B20]

The FITC Anti-Human CD20 Antibody (BCA-B20) from Assay Genie is a high-quality antibody designed for research involving CD20, a cell surface marker found on B cells. This antibody is conjugated with FITC (Fluorescein Isothiocyanate), allowing for direct fluorescence-based detection and analysis of CD20 expression in human samples. The FITC Anti-Human CD20 Antibody (BCA-B20) is raised in rabbits and extensively validated for use in flow cytometry, immunofluorescence, and immunohistochemistry applications. It specifically binds to the CD20 protein, enabling precise identification and characterization of B cells expressing this marker in various cell types and tissues. This antibody is suitable for a wide range of research areas, including immunology, oncology, and autoimmune diseases.

CD20 is a well-known marker for B cells and is often targeted in therapies for B cell-related disorders, making the FITC Anti-Human CD20 Antibody (BCA-B20) a valuable tool for investigating B cell biology and function. Researchers can use this antibody to study B cell development, activation, differentiation, and targeting for therapeutic interventions in diseases such as lymphoma, leukemia, and autoimmune conditions.In summary, the FITC Anti-Human CD20 Antibody (BCA-B20) from Assay Genie provides reliable and accurate detection of CD20-expressing B cells, making it an essential reagent for studies aiming to understand the role of B cells in health and disease.

Product Title:FITC Anti-Human CD20 Antibody [BCA/B20]
SKU:AGEL2812
Size:20 Tests, 100 Tests, 200 Tests
Clone No:BCA/B20
Synonyms:B-lymphocyte antigen CD20;MS4A1;B-lymphocyte surface antigen B1;Bp35;Leukocyte surface antigen Leu-16;Membrane-spanning 4-domains subfamily A member 1;MS4A1;CD20;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG2a, κ
Isotype Control:FITC Mouse IgG2a, κ Isotype Control[C1.18.4]
Form:Liquid
Conjugation:FITC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P11836
Gene ID:931
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD20 is a 33-37 kD, four transmembrane spanning protein, also known as B1 and Bp35. CD20 is expressed on pre-B-cells, resting and activated B cells (not plasma cells), some follicular dendritic cells, and at low levels on a T cell subset. CD20 is heavily phosphorylated on activated B cells and malignant B cells. Homo-oligomeric complexes of CD20 are thought to form Ca2+ conductive ion channels in the plasma membrane of B cells. The CD20 molecule is involved in B-cell activation and is associated with various Src family kinases (Lyn, Lck, Fyn). It exists in a complex with MHC class I and II, CD53, CD81, and CD82.

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