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FITC Anti-Human CD62L Antibody [HI62L] (AGEL3484)

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SKU AGEL3484
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FCM
Reactivity Human
Host Species Mouse
Isotype Mouse IgG2a, k
Clone HI62L
Conjugation FITC
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Description

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FITC Anti-Human CD62L Antibody [HI62L]

The FITC Anti-Human CD62L Antibody (HI62L) offered by AssayGenie is a premium-quality antibody designed for research applications involving CD62L, a cell surface molecule known as L-selectin. This antibody is raised in rabbits and is highly specific for human samples, making it a reliable tool for various immunological studies. CD62L, also known as L-selectin, is a crucial adhesion molecule involved in the migration of lymphocytes to secondary lymphoid organs. Its role in immune cell trafficking and homing makes it a key target for investigation in fields such as immunology, inflammation, and cancer research. The FITC-conjugated antibody enables easy detection and visualization of CD62L in cells, providing valuable insights into its expression and function.

Researchers can utilize the FITC Anti-Human CD62L Antibody (HI62L) in flow cytometry, immunofluorescence, and other assays to explore the role of CD62L in immune responses, inflammatory processes, and disease states. This antibody is validated for its specificity and sensitivity, ensuring reliable and reproducible results in experimental settings. Enhance your research with the AssayGenie FITC Anti-Human CD62L Antibody (HI62L) and unlock new possibilities in understanding immune cell behavior and function.

Product Title:FITC Anti-Human CD62L Antibody [HI62L]
SKU:AGEL3484
Size:20 Tests, 100 Tests, 200 Tests
Clone No:HI62L
Synonyms:L-selectin;Sell;CD62 antigen-like family member L;LAM-1;LECAM1;Lymph node homing receptor;Ly-22; CD62L;Lnhr;Ly22;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG2a, κ
Isotype Control:FITC Mouse IgG2a, κ Isotype Control[C1.18.4]
Form:Liquid
Conjugation:FITC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P14151
Gene ID:6402
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD62L is a 74-95 kD single chain type I glycoprotein referred to as L-selectin or LECAM-1. It is expressed on most peripheral blood B cells, subsets of T and NK cells, monocytes, granulocytes, and certain hematopoietic malignant cells. CD62L binds to carbohydrates present on certain glycoforms of CD34, glycam-1, and MAdCAM-1 and with a low affinity to anionic oligosaccharide sequences related to sialylated Lewis X (sLex, CD15s) through its C-type lectin domain. CD62L is important for the homing of naïve lymphocytes to high endothelial venules in peripheral lymph nodes and Peyer's patches. It also plays a role in leukocyte rolling on activated endothelial cells.

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