The FKBP6 Antibody (CAB7013) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, generated in rabbits, exhibits high specificity and sensitivity towards FKBP6 in human samples, making it ideal for Western blot applications. By binding to FKBP6, this antibody enables the detection and analysis of the protein in various cell types, making it an essential tool for studies in molecular biology and protein function.FKBP6, also known as FK506-binding protein 36, plays a crucial role in protein folding and intracellular trafficking processes, making it a potential target for therapeutic interventions in diseases such as cancer and neurodegenerative disorders.
This antibody is validated for use in WB, IF/ICC, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
FKBP6 Antibody
SKU:
CAB7013
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
FKBP36, SPGF77, FKBP6
Positive Sample:
SW620, Mouse heart, Mouse liver, Rat testis, Rat heart
Cellular Localization:
Chromosome, Cytoplasm, Nucleus, Cytosol.
Calculated MW:
37kDa
Observed MW:
37kDa
The protein encoded by this gene is a cis-trans peptidyl-prolyl isomerase that may function in immunoregulation and basic cellular processes involving protein folding and trafficking. This gene is located in a chromosomal region that is deleted in Williams-Beuren syndrome. Defects in this gene may cause male infertility. There are multiple pseudogenes for this gene located nearby on chromosome 7. Alternative splicing results in multiple transcript variants.
Purification Method
Affinity purification
Gene ID
8468
RRID
AB_2767569
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using FKBP6 Rabbit pAb (CAB7013) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 5s.
Immunofluorescence analysis of A-549 cells using FKBP6 Rabbit pAb (CAB7013). Secondary antibody: Cy3-conjugated Goat anti-Rabbit IgG (H+L) (CABS007) at 1:500 dilution. Blue: DAPI for nuclear staining.