The FUK Antibody (CAB17268) is a high-quality antibody developed for reliable detection and analysis of target proteins. This rabbit polyclonal antibody is highly specific and reacts strongly with human samples, making it an ideal tool for Western blot analysis.FUK, also known as fucose kinase, plays a crucial role in the glycosylation process, where it catalyzes the phosphorylation of fucose to produce GDP-Fucose. This molecule is important for the synthesis of glycoproteins and glycolipids, which are involved in cell signaling, immune response, and other vital functions.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse samples.
Product Name:
FUK Antibody
SKU:
CAB17268
Size:
20μL, 100μL
Reactivity:
Human, Mouse
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
FUK, CDGF2, 1110046B12Rik
Positive Sample:
U-87MG, Mouse brain, Mouse kidney
Cellular Localization:
Cytosol.
Calculated MW:
118kDa
Observed MW:
117kDa
The protein encoded by this gene belongs to the GHMP (galacto-, homoserine, mevalonate and phosphomevalonate) kinase family and catalyzes the phosphorylation of L-fucose to form beta-L-fucose 1-phosphate. This enzyme catalyzes the first step in the utilization of free L-fucose in glycoprotein and glycolipid synthesis. L-fucose may be important in mediating a number of cell-cell interactions such as blood group antigen recognition, inflammation, and metastatis. While several transcript variants may exist for this gene, the full-length nature of only one has been described to date.
Purification Method
Affinity purification
Gene ID
197258
RRID
AB_2769532
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using FUK Rabbit pAb (CAB17268) at 1:3000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 30s.
