The GABRA3 Antibody (CAB11636) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, is highly sensitive in detecting Gabra3 in human samples and has been validated for use in Western blot applications.Gabra3 is known for its involvement in mediating the effects of the neurotransmitter gamma-aminobutyric acid (GABA) in the brain, making it a key player in the regulation of inhibitory neurotransmission. Dysregulation of Gabra3 has been linked to various neurological disorders, including epilepsy, anxiety disorders, and alcohol addiction.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
GABRA3 Antibody
SKU:
CAB11636
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified.
Purification Method
Affinity purification
Gene ID
2556
RRID
AB_2758655
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using GABRA3 Rabbit pAb (CAB11636) at 1:3000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 30s.
