The Gag Monoclonal Antibody (PACO34646) is a cutting-edge tool for research in virology, specifically targeting the Gag protein involved in viral assembly and packaging. This monoclonal antibody, developed through careful selection and validation processes, offers high specificity and sensitivity for detecting Gag protein in various sample types.The Gag protein is essential for the formation of viral particles, making it a key target for studying viral replication and pathogenesis. By using this antibody in techniques such as Western blot and immunofluorescence, researchers can elucidate the mechanisms underlying viral assembly and identify potential therapeutic strategies to disrupt viral replication.
With its superior performance in detecting Gag protein, the PACO34646 monoclonal antibody is a valuable tool for researchers investigating retroviruses and other Gag-containing viruses. Its application extends to fields such as molecular biology, infectious diseases, and antiviral drug development, providing crucial insights into viral pathogenesis and potential targets for intervention.
Antibody Name:
gag Antibody (PACO34646)
Antibody SKU:
PACO34646
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA
Recommended Dilutions:
Species Reactivity:
Moloney murine leukemia virus
Immunogen:
Recombinant Moloney murine leukemia virus Gag polyprotein protein (216-478AA)
Gag polyprotein plays a role in budding and is processed by the viral protease during virion maturation outside the cell. During budding, it recruits, in a PPXY-dependent or independent manner, Nedd4-like ubiquitin ligases that conjugate ubiquitin molecules to Gag, or to Gag binding host factors. Interaction with HECT ubiquitin ligases probably link the viral protein to the host ESCRT pathway and facilitate release.
Synonyms:
Gag polyprotein (Pr65gag) (Core polyprotein) [Cleaved into: Matrix protein p15 (MA); RNA-binding phosphoprotein p12 (pp12); Capsid protein p30 (CA); Nucleocapsid protein p10-Gag (NC-gag)], gag
UniProt Protein Function:
Gag polyprotein plays a role in budding and is processed by the viral protease during virion maturation outside the cell. During budding, it recruits, in a PPXY-dependent or independent manner, Nedd4-like ubiquitin ligases that conjugate ubiquitin molecules to Gag, or to Gag binding host factors. Interaction with HECT ubiquitin ligases probably link the viral protein to the host ESCRT pathway and facilitate release.
