The GB Antibody (PAC050390) is a polyclonal antibody developed for research on GB, a protein involved in immune regulation and inhibiting immune responses. This antibody, produced in rabbits, is highly reactive with human samples and is validated for Western blot applications. By binding to the GB protein, this antibody enables the detection and analysis of GB in various cell types, making it an essential tool for studies in immunology and cancer research.GB, also known as an immune inhibitory receptor, plays a crucial role in immune homeostasis by regulating inflammation and inhibiting allergic reactions.
Its importance in modulating immune responses makes it a valuable target for research into diseases such as cancer, autoimmune disorders, and chronic inflammatory conditions. Understanding the function of GB is essential for the development of therapies that can regulate or enhance immune function in these disease contexts.
Antibody Name:
gB Antibody (PACO50390)
Antibody SKU:
PACO50390
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA
Recommended Dilutions:
Species Reactivity:
Human herpesvirus 2
Immunogen:
Recombinant Human herpesvirus 2 Envelope glycoprotein B protein (23-279AA)
Envelope glycoprotein that forms spikes at the surface of virion envelope. Essential for the initial attachment to heparan sulfate moities of the host cell surface proteoglycans. Involved in fusion of viral and cellular membranes leading to virus entry into the host cell. Following initial binding to its host receptors, membrane fusion is mediated by the fusion machinery composed at least of gB and the heterodimer gH/gL. May be involved in the fusion between the virion envelope and the outer nuclear membrane during virion egress.
Synonyms:
Envelope glycoprotein B (gB), gB
UniProt Protein Function:
Envelope glycoprotein that forms spikes at the surface of virion envelope. Essential for the initial attachment to heparan sulfate moities of the host cell surface proteoglycans. Involved in fusion of viral and cellular membranes leading to virus entry into the host cell. Following initial binding to its host receptors, membrane fusion is mediated by the fusion machinery composed at least of gB and the heterodimer gH/gL. May be involved in the fusion between the virion envelope and the outer nuclear membrane during virion egress.
