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GenieFluor 488 Anti-Human CD73 Antibody [AD2] (AGEL2776)

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SKU AGEL2776
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FCM
Reactivity Human
Host Species Mouse
Isotype Mouse IgG1, κ
Clone AD2
Conjugation AF488
€144 - €532
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Description

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GenieFluor 488 Anti-Human CD73 Antibody [AD2]

The GENIEFLUOR 488 Anti-Human CD73 Antibody (AD2) from Assay Genie is a cutting-edge tool for researchers studying CD73, a cell surface protein known for its role in immune response modulation and inflammation regulation. This highly specific antibody, optimized for human samples, is essential for detecting and analyzing CD73 expression in various cell types. Validated for multiple applications including immunofluorescence and flow cytometry, the GENIEFLUOR 488 Anti-Human CD73 Antibody (AD2) provides accurate, reliable results for studies in immunology, oncology, and other related fields.

CD73, also referred to as ecto-5'-nucleotidase, is a key enzyme involved in purinergic signaling and adenosine production. Its diverse functions in immune regulation, cancer progression, and inflammatory responses make it a pivotal target for therapeutic interventions and biomarker discovery. By using the GENIEFLUOR 488 Anti-Human CD73 Antibody (AD2), researchers can delve deeper into the intricate mechanisms involving CD73, paving the way for innovative research advancements and potential clinical applications.

Product Title:GenieFluor 488 Anti-Human CD73 Antibody [AD2]
SKU:AGEL2776
Size:20 Tests, 100 Tests, 200 Tests
Clone No:AD2
Synonyms:Ecto-5'-nucleotidase; E.C3.1.3.5; L-VAP-2; NT5E; 5'-NT;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:Genie Fluor 488 Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:Genie Fluor488
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P21589
Gene ID:4907
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD73 is a 70 kD glycophosphatidylinositol (GPI)-linked 5'-nucleotidase, which is also known as ecto-5'-nucleotidase. It converts adenosine monophosphate (AMP) to adenosine. CD73 is expressed on subsets of T and B cells, mesenchymal stem cells, follicular dendritic cells, endothelial cells, and epithelial cells. It has been reported that CD73 costimulates T cell activation, and mediates adhesion of lymphocytes to follicular dendritic cells and endothelial cells.

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