The GLUT3/SLC2A3 Monoclonal Antibody (CAB4137) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody is produced using rabbit monoclonal technology, ensuring high specificity and sensitivity in detecting GLUT3 expression in various biological samples. GLUT3 is known for its high affinity for glucose and its role in facilitating glucose transport across cell membranes, particularly in tissues with high energy demands such as the brain and red blood cells. Dysregulation of GLUT3 expression has been linked to metabolic disorders, neurodegenerative diseases, and cancer, making it a valuable target for research in these areas.
This antibody is validated for use in WB, IP, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
GLUT3/SLC2A3 Monoclonal Antibody
SKU:
CAB4137
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Clone Number:
ARC0917
Conjugate:
Unconjugated
Immunogen:
Synthetic peptide. This information is considered to be commercially sensitive.
Enables dehydroascorbic acid transmembrane transporter activity; glucose binding activity; and glucose transmembrane transporter activity. Involved in glucose import across plasma membrane and transport across blood-brain barrier. Is integral component of plasma membrane. Biomarker of Alzheimer's disease; acanthosis nigricans; diabetes mellitus; and type 2 diabetes mellitus.
Purification Method
Affinity purification
Gene ID
6515
RRID
AB_2863194
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using GLUT3/SLC2A3 Rabbit mAb (CAB4137) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 1s.
Immunoprecipitation analysis of 600 μg extracts of Mouse brain using 3 μg GLUT3/SLC2A3 antibody (CAB4137). Western blot was performed from the immunoprecipitate using GLUT3/SLC2A3 antibody (CAB4137) at a dilution of 1:1000.
