Description
| Product Name: | Human CABP7 Recombinant Protein |
| Product Code: | RPPB2958 |
| Size: | 5µg |
| Species: | Human |
| Target: | CABP7 |
| Synonyms: | Calcium-binding protein 7, CaBP7, Calneuron II, Calneuron-2, CABP7, CALN2. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile filtered colorless solution. |
| Formulation: | CABP7 protein solution (0.5mg/ml) containing Phosphate-buffered saline (pH 7.4). |
| Stability: | CABP7 Human Recombinant although stable at 4°C for 1 week, should be stored below -18°C. Please prevent freeze thaw cycles. |
| Purity: | Greater than 80.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MPFHPVTAAL MYRGIYTVPN LLSEQRPVDI PEDELEEIRE AFKVFDRDGN GFISKQELGT AMRSLGYMPN EVELEVIIQR LDMDGDGQVD FEEFVTLLGP KLSTSGIPEK FHGTDFDTVF WKCDMQKLTV DELKRLLYDT FCEHLSMKDI ENIIMTEEES HLGTAEECPV DVETCSNQQI RQTCVRKS |
Calcium-binding protein 7 (CABP7) contains 2 EF-hand domains. CABP7 negatively regulates Golgi-to-plasma membrane trafficking by interacting with PI4KB and inhibiting its activity. The CaBP family of EF-hand containing small Ca (2+)-binding proteins has lately emerged as significant regulators of multiple targets essential to normal neuronal function in the mammalian central nervous system.
CABP7 produced in E.Coli is a single, non-glycosylated polypeptide chain containing 208 amino acids (1-188 a.a.) and having a molecular mass of 23.7kDa.CABP7 is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| UniProt Protein Function: | CABP7: Negatively regulates Golgi-to-plasma membrane trafficking by interacting with PI4KB and inhibiting its activity. |
| UniProt Protein Details: | Protein type:Membrane protein, integral Chromosomal Location of Human Ortholog: 22q12.2 Cellular Component: perinuclear region of cytoplasm; integral to membrane; plasma membrane; trans-Golgi network membrane Molecular Function:calcium ion binding |
| UniProt Code: | Q86V35 |
| NCBI GenInfo Identifier: | 32698884 |
| NCBI Gene ID: | 164633 |
| NCBI Accession: | NP_872333 |
| UniProt Related Accession: | Q86V35 |
| Molecular Weight: | 24,453 Da |
| NCBI Full Name: | calcium-binding protein 7 |
| NCBI Synonym Full Names: | calcium binding protein 7 |
| NCBI Official Symbol: | CABP7�� |
| NCBI Official Synonym Symbols: | CALN2�� |
| NCBI Protein Information: | calcium-binding protein 7; calneuron 2; calneuron-2; calneuron II |
| UniProt Protein Name: | Calcium-binding protein 7 |
| UniProt Synonym Protein Names: | Calneuron II; Calneuron-2 |
| Protein Family: | Calcium-binding protein |
| UniProt Gene Name: | CABP7�� |
| UniProt Entry Name: | CABP7_HUMAN |
