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Key Features

PE Anti-Human CD11a Antibody [TS1/22.1.1.13] (AGEL0235)

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SKU AGEL0235
Product Type Antibody
Antibody Type Monoclonal Antibody
Reactivity Human
Host Species Mouse
Isotype IgG1
Clone TS1/22.1.1.13
Conjugation PE
Applications FC
€48 - €203
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Description

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PE Anti-Human CD11a Antibody [TS1/22.1.1.13]

The Human CD11a Monoclonal Antibody (PE Conjugated, TS1/22) is a powerful tool for researchers studying cell adhesion molecules and immune system function. This antibody specifically targets CD11a, a key integrin involved in leukocyte migration and activation. With its PE conjugation, this antibody allows for easy visualization and quantification of CD11a-expressing cells using flow cytometry or fluorescence microscopy.CD11a plays a crucial role in a wide range of immune responses, including T cell activation, leukocyte recruitment to sites of inflammation, and immune surveillance. Dysregulation of CD11a expression or function has been implicated in various inflammatory and autoimmune diseases, making it a promising target for therapeutic intervention.

With its high specificity and sensitivity, the Human CD11a Monoclonal Antibody (PE Conjugated, TS1/22) from AssayGenie provides researchers with a reliable tool for investigating the role of CD11a in health and disease. Whether studying immune cell interactions, inflammatory processes, or therapeutic targeting strategies, this antibody offers valuable insights into the complex mechanisms of the immune system. Trust AssayGenie for quality antibodies that accelerate your research endeavors.

Product Title:PE Anti-Human CD11a Antibody [TS1/22.1.1.13]
SKU:AGEL0235
Size:20 Tests, 100 Tests, 200 Tests
Clone No:TS1/22.1.1.13
Synonyms:Integrin alpha-L;Itgal;CD11 antigen-like family member A;LFA-1A;Lymphocyte antigen 15;Ly-15;CD11a;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:PE Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:PE
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P20701
Gene ID:3683
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD11a is a 170-180 kD type I transmembrane glycoprotein also known as LFA-1α chain and integrin αL subunit. CD11a non-covalently associates with integrin β2 (CD18) to form LFA-1. It is expressed on all leukocytes, including B and T lymphocytes, monocytes, macrophages, neutrophils, basophils and eosinophils. It is absent on non-hematopoietic tissues and platelets. CD11a plays a central role in leukocyte cell-cell interactions and is important in lymphocyte costimulation. CD11a/CD18 binds to ICAM-1 (CD54), ICAM-2 (CD102), and ICAM-3 (CD50).

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