Human CD300E Recombinant Protein (RPPB3116)
- SKU:
- RPPB3116
- Product Type:
- Recombinant Protein
- Species:
- Human
- Uniprot:
- Q496F6
- Research Area:
- CD Antigens
Description
| Product Name: | Human CD300E Recombinant Protein |
| Product Code: | RPPB3116 |
| Size: | 20µg |
| Species: | Human |
| Target: | CD300E |
| Synonyms: | CD300e Molecule, CD300e Antigen, CD300LE, IREM2, CLM2, Immune Receptor Expressed On Myeloid Cells 2, Polymeric Immunoglobulin Receptor 2,CD300 Antigen Like Family Member E, CD300 Antigen-Like Family Member E,Poly-Ig Receptor 2, CMRF35-A5, PIgR2, CMRF35-Like Molecule 2, CMRF35A5, CD300E. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered clear solution. |
| Formulation: | CD300E protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH8.0). |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 90.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSLKGPGSV TGTAGDSLTV WCQYESMYKG YNKYWCRGQY DTSCESIVET KGEEKVERNG RVSIRDHPEA LAFTVTMQNL NEDDAGSYWC KIQTVWVLDS WSRDPSDLVR VYVSPAITTP RRTTHPATPP IFLVVNPGRN LSTGEVLTQN SGFRLSSPH |
CMRF35-like molecule 2 precursor (CD300E) is a member of the CD300 family. CD300E is a 205 amino acid single-pass type I membrane protein which contains one Ig-like V-type (immunoglobulin-like) domain. While interacting with DAP12, CD300E probably performs as an activating receptor. CD300E is present on the surface of mature hematopoietic cells of the monocyte & myeloid lineages.
CD300E Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 179 amino acids (18-173 a.a) and having a molecular mass of 19.9kDa.CD300E is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| UniProt Protein Function: | CD300E: Probably acts as an activating receptor. Belongs to the CD300 family. |
| UniProt Protein Details: | Protein type:Receptor, misc.; Membrane protein, integral Chromosomal Location of Human Ortholog: 17q25.1 Cellular Component: plasma membrane Biological Process: innate immune response; regulation of immune response |
| NCBI Summary: | This gene encodes a member of the CD300 glycoprotein family of cell surface proteins expressed on myeloid cells. The protein interacts with the TYRO protein tyrosine kinase-binding protein and is thought to act as an activating receptor. [provided by RefSeq, Nov 2012] |
| UniProt Code: | Q496F6 |
| NCBI GenInfo Identifier: | 296434454 |
| NCBI Gene ID: | 342510 |
| NCBI Accession: | Q496F6.2 |
| UniProt Secondary Accession: | Q496F6,Q7Z7I3, B4DNS1, |
| UniProt Related Accession: | Q496F6 |
| Molecular Weight: | 22,918 Da |
| NCBI Full Name: | CMRF35-like molecule 2 |
| NCBI Synonym Full Names: | CD300e molecule |
| NCBI Official Symbol: | CD300E�� |
| NCBI Official Synonym Symbols: | CLM2; CLM-2; IREM2; PIgR2; IREM-2; PIgR-2; CD300LE; CMRF35-A5�� |
| NCBI Protein Information: | CMRF35-like molecule 2 |
| UniProt Protein Name: | CMRF35-like molecule 2 |
| UniProt Synonym Protein Names: | CD300 antigen-like family member E; CMRF35-A5; Immune receptor expressed on myeloid cells 2; IREM-2; Polymeric immunoglobulin receptor 2; PIgR-2; PIgR2; Poly-Ig receptor 2; CD_antigen: CD300e |
| Protein Family: | CMRF35-like molecule |
| UniProt Gene Name: | CD300E�� |
| UniProt Entry Name: | CLM2_HUMAN |
