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PerCP/Cyanine5.5 Anti-Human CD45 Antibody [HI30] (AGEL1684)

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SKU AGEL1684
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FC
Reactivity Human
Host Species Mouse
Isotype IgG2a,k
Clone HI30
Conjugation PerCP/Cy5.5
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Description

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PerCP/Cyanine5.5 Anti-Human CD45 Antibody [HI30]

The Human CD45 Monoclonal Antibody (PERCP/Cyanine5.5 Conjugated, Clone HI30, [AGEL1684]) offered by Assay Genie is a cutting-edge tool designed for precise identification and analysis of CD45, a key cell surface marker involved in immune cell function. This monoclonal antibody, conjugated with PERCP/Cyanine5.5, excels in flow cytometry and other immunophenotyping methods, enabling high-resolution detection of CD45 expression levels in diverse cell populations.CD45, a tyrosine phosphatase expressed on most immune cells, plays a pivotal role in lymphocyte development, activation, and signaling processes. The HI30 clone specifically recognizes human CD45 isoforms, making it a versatile tool for investigating immune cell subsets, monitoring immune responses, and studying diseases characterized by immune dysregulation.

By targeting CD45 with precision and sensitivity, researchers can gain deeper insights into immune cell dynamics, immune-mediated pathologies, and therapeutic interventions aimed at modulating immune responses. Trust in the reliability and performance of the Human CD45 Monoclonal Antibody (PERCP/Cyanine5.5 Conjugated, Clone HI30, [AGEL1684]) from Assay Genie for robust and insightful immunological research.

Product Title:PerCP/Cyanine5.5 Anti-Human CD45 Antibody [HI30]
SKU:AGEL1684
Size:20 Tests, 100 Tests, 200 Tests
Clone No:HI30
Synonyms:Receptor-type tyrosine-protein phosphatase C;Ptprc;L-CA;Ly-5;T200;CD45;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:PerCP/Cyanine5.5 Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:PerCP/Cyanine 5.5
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P08575
Gene ID:5788
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD45 is a 180 - 240 kD single chain type I membrane glycoprotein also known as leukocyte common antigen (LCA) and T200. It is a tyrosine phosphatase expressed on the plasma membrane of all hematopoietic cells, except erythrocytes or platelets. CD45 is a signaling molecule that regulates a variety of cellular processes including cell growth, differentiation, cell cycle, and oncogenic transformation. CD45 plays a critical role in T and B cell antigen receptor-mediated activation by dephosphorylating substrates including p56Lck, p59Fyn, and other Src family kinases. CD45 non-covalently associates with lymphocyte phosphatase-associated phosphoprotein (LPAP) on T and B lymphocytes. CD45 has been reported to bind galectin-1 and to be associated with several other cell surface antigens including CD1, CD2, CD3, and CD4.

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