Human CD90 Recombinant Protein (RPPB3100)
- SKU:
- RPPB3100
- Product Type:
- Recombinant Protein
- Species:
- Human
- Uniprot:
- P04216
- Research Area:
- CD Antigens
Description
| Product Name: | Human CD90 Recombinant Protein |
| Product Code: | RPPB3100 |
| Size: | 5µg |
| Species: | Human |
| Target: | CD90 |
| Synonyms: | Thy-1 Cell Surface Antigen, Thy-1 Antigen, CDw90, Thy-1 Membrane Glycoprotein, Thy-1 T-Cell Antigen, CD90 Antigen, CD90, THY1. |
| Source: | Sf9 Insect cells |
| Physical Appearance: | Sterile filtered colorless solution. |
| Formulation: | CD90 protein solution (0.25mg/ml) contains Phosphate Buffered Saline (pH7.4) and 10% glycerol. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 95.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | QKVTSLTACL VDQSLRLDCR HENTSSSPIQ YEFSLTRETK KHVLFGTVGV PEHTYRSRTN FTSKYNMKVL YLSAFTSKDE GTYTCALHHS GHSPPISSQN VTVLRDKLVK CHHHHHH |
Thy-1 membrane glycoprotein (CD90) is a cell membrane protein which contains one lg-like V-type (immunoglobulin-like) domain. CD90 protein belongs to the immunoglobulin superfamily of adhesion molecules with constitutive expression on fibroblast cells. CD90 protein is involved in cell adhesion and cell communication in numerous cell types, predominantly in cells of the immune and nervous systems. CD90 may also have a role in cell-cell or cell-ligand interactions during synaptogenesis and other events in the brain. CD90 can be used as a marker for various stem cells and for the axonal processes of mature neurons. CD90 may serve as a tumor suppressor in nasopharyngeal carcinoma.
CD90 Human Recombinant produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 117 amino acids (20-130a.a.) and having a molecular mass of 13.3kDa (Molecular size on SDS-PAGE will appear at approximately 13.5-28kDa).CD90 is fused with a 6 amino acids His tag at C-Terminus and purified by proprietary chromatographic techniques.
| UniProt Protein Function: | THY1: May play a role in cell-cell or cell-ligand interactions during synaptogenesis and other events in the brain. |
| UniProt Protein Details: | Protein type:Cell adhesion; Motility/polarity/chemotaxis; Membrane protein, GPI anchor Chromosomal Location of Human Ortholog: 11q23.3 Cellular Component: anchored to external side of plasma membrane; focal adhesion; growth cone; integral to plasma membrane; endoplasmic reticulum; dendrite; apical plasma membrane; plasma membrane; cytosol; lipid raft; external side of plasma membrane Molecular Function:integrin binding; protein binding; protein kinase binding Biological Process: focal adhesion formation; negative regulation of T cell receptor signaling pathway; cytoskeleton organization and biogenesis; T cell receptor signaling pathway; cell-cell adhesion; retinal cone cell development; negative regulation of protein kinase activity; negative regulation of axonogenesis; positive regulation of T cell activation; angiogenesis; positive regulation of release of sequestered calcium ion into cytosol; negative regulation of cell migration; positive regulation of GTPase activity |
| NCBI Summary: | This gene encodes a cell surface glycoprotein and member of the immunoglobulin superfamily of proteins. The encoded protein is involved in cell adhesion and cell communication in numerous cell types, but particularly in cells of the immune and nervous systems. The encoded protein is widely used as a marker for hematopoietic stem cells. This gene may function as a tumor suppressor in nasopharyngeal carcinoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2015] |
| UniProt Code: | P04216 |
| NCBI GenInfo Identifier: | 20455514 |
| NCBI Gene ID: | 7070 |
| NCBI Accession: | P04216.2 |
| UniProt Secondary Accession: | P04216,Q16008, Q9NSP1, |
| UniProt Related Accession: | P04216 |
| Molecular Weight: | 17,935 Da |
| NCBI Full Name: | Thy-1 membrane glycoprotein |
| NCBI Synonym Full Names: | Thy-1 cell surface antigen |
| NCBI Official Symbol: | THY1�� |
| NCBI Official Synonym Symbols: | CD90�� |
| NCBI Protein Information: | thy-1 membrane glycoprotein; CDw90; thy-1 antigen; Thy-1 T-cell antigen |
| UniProt Protein Name: | Thy-1 membrane glycoprotein |
| UniProt Synonym Protein Names: | CDw90; Thy-1 antigen; CD_antigen: CD90 |
| Protein Family: | Thy-1 membrane glycoprotein |
| UniProt Gene Name: | THY1�� |
| UniProt Entry Name: | THY1_HUMAN |
