Human Cyclophilin C Recombinant Protein (RPPB1538)
- SKU:
- RPPB1538
- Product Type:
- Recombinant Protein
- Species:
- Human
- Uniprot:
- P45877
- Research Area:
- Enzymes
Frequently bought together:
Description
| Product Name: | Human Cyclophilin C Recombinant Protein |
| Product Code: | RPPB1538 |
| Size: | 10µg |
| Species: | Human |
| Target: | Cyclophilin C |
| Synonyms: | Peptidylprolyl Isomerase C (Cyclophilin C), Cyclophilin C, Rotamase C, EC 5.2.1.8, PPIase C, CYPC, Peptidyl-Prolyl Cis-Trans Isomerase C, Parvulin, PPIC. |
| Source: | Escherichia Coli |
| Physical Appearance: | Filtered White lyophilized (freeze-dried) powder. |
| Formulation: | Cyclophilin-C was filtered (0.4 �m) and lyophilized in 20mM Tris buffer and 50mM NaCl, pH 7.5. |
| Solubility: | It is recommended to add 200�l of deionized water to prepare a working stock solution of approximately 0.5mg/ml and let the lyophilized pellet dissolve completely. Cyclophilin-C is not sterile! Please filter the product by an appropriate sterile filter before using it in the cell culture. |
| Stability: | Store lyophilized protein at -20°C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted protein can be stored at 4°C for a limited period of time; it does not show any change after two weeks at 4°C. |
| Purity: | Greater than 95.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MKHHHHHHASFRKRGPSVTA KVFFDVRIGD KDVGRIVIGL FGKVVPKTVE NFVALATGEK GYGYKGSKFH RVIKDFMIQG GDITTGDGTG GVSIYGETFP DENFKLKHYG IGWVSMANAG PDTNGSQFFI TLTKPTWLDG KHVVFGKVID GMTVVHSIEL QATDGHDRPL TNCSIINSGK IDVKTPFVVE IADW |
Cyclophilin-C belongs to the peptidyl-prolyl cis-trans isomerase (PPIase)) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. Like other PPIases, the Cyclophilin-C protein can bind immunosuppressant cyclosporin A.
Cyclophilin-C Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain (Phe29-Trp212) containing 194 amino acids including a 10 aa His tag at N-terminus. The total calculated molecular mass is 21.3kDa.
| UniProt Protein Function: | PPIC: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Belongs to the cyclophilin-type PPIase family. |
| UniProt Protein Details: | Protein type:EC 5.2.1.8; Isomerase; Cyclophilin Chromosomal Location of Human Ortholog: 5q23.2 Molecular Function:cyclosporin A binding; peptidyl-prolyl cis-trans isomerase activity; protein binding |
| NCBI Summary: | The protein encoded by this gene is a member of the peptidyl-prolyl cis-trans isomerase (PPIase)) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. Similar to other PPIases, this protein can bind immunosuppressant cyclosporin A. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P45877 |
| NCBI GenInfo Identifier: | 1169178 |
| NCBI Gene ID: | 5480 |
| NCBI Accession: | P45877.1 |
| UniProt Secondary Accession: | P45877,A4LBB5, |
| UniProt Related Accession: | P45877 |
| Molecular Weight: | 22,763 Da |
| NCBI Full Name: | Peptidyl-prolyl cis-trans isomerase C |
| NCBI Synonym Full Names: | peptidylprolyl isomerase C |
| NCBI Official Symbol: | PPIC�� |
| NCBI Official Synonym Symbols: | CYPC�� |
| NCBI Protein Information: | peptidyl-prolyl cis-trans isomerase C |
| UniProt Protein Name: | Peptidyl-prolyl cis-trans isomerase C |
| UniProt Synonym Protein Names: | Cyclophilin C; Rotamase C |
| Protein Family: | Peptidyl-prolyl cis-trans isomerase |
| UniProt Gene Name: | PPIC�� |
| UniProt Entry Name: | PPIC_HUMAN |
