Human LGALS13 Recombinant Protein (RPPB0292)
- SKU:
- RPPB0292
- Product Type:
- Recombinant Protein
- Species:
- Human
- Uniprot:
- Q9UHV8
- Research Area:
- Growth Factors & Cytokines
Description
| Product Name: | Human LGALS13 Recombinant Protein |
| Product Code: | RPPB0292 |
| Size: | 100µg |
| Species: | Human |
| Target: | LGALS13 |
| Synonyms: | Galactoside-binding soluble lectin 13, Galectin-13, Gal-13, Placental tissue protein 13, PP13, Placental protein 13, LGALS13, PLAC8, GAL13. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered colorless solution. |
| Formulation: | LGALS13 protein solution (0.5mg/ml) is formulated in 1xPBS buffer pH 7.4. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks.Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 90.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | macglvasnl nlkpgeclrv rgevapdaks fvlnlgkdsn nlclhfnprf nahgdantiv cnskdggawg teqreavfpf qpgsvaevci tfdqanltvk lpdgyefkfp nrlnleainy maadgdfkik cvafd |
Recombinant Galectin-13 is an E. coli expressed peptide, this protein is one of human placenta specific galectins, like all galectin family, it contains a carbohydrate recognition domain (CRD) as well. Increased blood concentration was found highly asscoaited with preeclampsia and HELLP syndrome in pregnant women. The molecular weight of galectin-13 is 16kDa.
Recombinant Human LGALS13 produced in E.Coli is a single, non-glycosylated polypeptide chain having a molecular mass of 16kDa. The LGALS13 also might appear as a homodimer, having a total Mw of 32kDa. LGALS13 is fused to a 6xHis tag at n-terminal and purified using standard chromatography techniques.
| UniProt Protein Function: | LGALS13: Has lysophospholipase activity. |
| UniProt Protein Details: | Protein type:Phospholipase; EC 3.1.1.5 Chromosomal Location of Human Ortholog: 19q13.1 Molecular Function:protein binding; carbohydrate binding; lysophospholipase activity Biological Process: apoptosis; phospholipid metabolic process |
| NCBI Summary: | Lysophospholipases are enzymes that act on biological membranes to regulate the multifunctional lysophospholipids. The protein encoded by this gene has lysophospholipase activity. It is composed of two identical subunits which are held together by disulfide bonds. This protein has structural similarity to several members of the beta-galactoside-binding S-type lectin family. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q9UHV8 |
| NCBI GenInfo Identifier: | 6650760 |
| NCBI Gene ID: | 29124 |
| NCBI Accession: | AAF22001.1 |
| UniProt Secondary Accession: | Q9UHV8,C5HZ15, |
| UniProt Related Accession: | Q9UHV8 |
| Molecular Weight: | Predicted Molecular Mass: 48.5kDaAccurate Molecular Mass: 44kDa as determined by SDS-PAGE reducing conditions. |
| NCBI Full Name: | placental protein 13 |
| NCBI Synonym Full Names: | lectin, galactoside-binding, soluble, 13 |
| NCBI Official Symbol: | LGALS13�� |
| NCBI Official Synonym Symbols: | PP13; GAL13; PLAC8�� |
| NCBI Protein Information: | galactoside-binding soluble lectin 13 |
| UniProt Protein Name: | Galactoside-binding soluble lectin 13 |
| UniProt Synonym Protein Names: | Galectin-13; Gal-13; Placental tissue protein 13; PP13; Placental protein 13 |
| Protein Family: | Placental protein |
| UniProt Gene Name: | LGALS13�� |
| UniProt Entry Name: | PP13_HUMAN |
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