Description
| Product Name: | Human MYL6 Recombinant Protein |
| Product Code: | RPPB4037 |
| Size: | 10µg |
| Species: | Human |
| Target: | MYL6 |
| Synonyms: | Myosin light polypeptide 6, 17 kDa myosin light chain, LC17, Myosin light chain 3, MLC-3, Myosin light chain alkali 3, Myosin light chain A3, Smooth muscle and nonmuscle myosin light chain alkali 6, MYL6, ESMLC, LC17A, LC17B, MLC1SM, MLC3NM, MLC3SM, LC17-GI, LC17-NM. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered colorless solution. |
| Formulation: | The MYL6 solution (0.5 mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 1mM DTT and 10% glycerol. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.�For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 90.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MCDFTEDQTA EFKEAFQLFD RTGDGKILYS QCGDVMRALG QNPTNAEVLK VLGNPKSDEM NVKVLDFEHF LPMLQTVAKN KDQGTYEDYV EGLRVFDKEG NGTVMGAEIR HVLVTLGEKM TEEEVEMLVA GHEDSNGCIN YEELVRMVLN G |
Myosin light polypeptide 6 (MYL6) is a hexameric ATPase cellular motor protein. MYL6 is composed of 2 heavy chains, 2 nonphosphorylatable alkali light chains, and 2o phosphorylatable regulatory light chains. MYL6 is a myosin alkali light chain which is expressed in smooth muscle and non-muscle tissues. MYL6 partakes in generating the force for cellular movements, thus having an imperative role in overall cellular function.
MYL6 Human Recombinant fused with a�20 amino acid His tag at N-terminus produced in E.Coli is a single, non-glycosylated, polypeptide chain containing�171 amino acids (1-151 a.a.) and having a molecular mass of 19.1kDa. The MYL6 is purified by proprietary chromatographic techniques.
| UniProt Protein Function: | MYL6: Regulatory light chain of myosin. Does not bind calcium. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Motility/polarity/chemotaxis; Motor Chromosomal Location of Human Ortholog: 12q13.2 Cellular Component: brush border; cytosol; extracellular matrix; membrane; myosin complex; unconventional myosin complex; vesicle Molecular Function:actin-dependent ATPase activity; motor activity; protein binding; structural constituent of muscle Biological Process: muscle contraction; muscle filament sliding; skeletal muscle development |
| NCBI Summary: | Myosin is a hexameric ATPase cellular motor protein. It is composed of two heavy chains, two nonphosphorylatable alkali light chains, and two phosphorylatable regulatory light chains. This gene encodes a myosin alkali light chain that is expressed in smooth muscle and non-muscle tissues. Genomic sequences representing several pseudogenes have been described and two transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P60660 |
| NCBI GenInfo Identifier: | 47606436 |
| NCBI Gene ID: | 4637 |
| NCBI Accession: | P60660.2 |
| UniProt Secondary Accession: | P60660,P16475, P24572, P24573, Q12790, Q561V9, Q6IAZ0 Q6IPY5, |
| UniProt Related Accession: | P60660 |
| Molecular Weight: | 17kDa |
| NCBI Full Name: | Myosin light polypeptide 6 |
| NCBI Synonym Full Names: | myosin light chain 6 |
| NCBI Official Symbol: | MYL6�� |
| NCBI Official Synonym Symbols: | LC17; ESMLC; LC17A; LC17B; MLC-3; MLC1SM; MLC3NM; MLC3SM; LC17-GI; LC17-NM�� |
| NCBI Protein Information: | myosin light polypeptide 6 |
| UniProt Protein Name: | Myosin light polypeptide 6 |
| UniProt Synonym Protein Names: | 17 kDa myosin light chain; LC17; Myosin light chain 3; MLC-3; Myosin light chain alkali 3; Myosin light chain A3; Smooth muscle and nonmuscle myosin light chain alkali 6 |
| Protein Family: | Myosin light polypeptide |
| UniProt Gene Name: | MYL6�� |
