Human P53 Recombinant Protein (hFc Tag) (HDPT0444)

SKU:
HDPT0444
Product Type:
Recombinant Protein
Host Species:
HEK293
Reactivity:
Human
€550

Description

Human P53 Recombinant Protein (hFc Tag)

Description:This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277). [provided by RefSeq, Dec 2016]
Product name:Human P53 Recombinant Protein (hFc Tag)
Synonyms:BCC7; BMFS5; LFS1; P53; TRP53
Type:protein
Size:50 µg
Name:P53
Origin:Human
Source:HEK293
Protein Type:Recombinant
Application:Contact Technical Support
Purity:Contact Technical Support
Purification:affinity purification
Format:Lyophilized
Conjugate:C-Human Fc
Storage:Store at -80°C for 12 months (Avoid repeated freezing and thawing)
Usage:Research use only
Buffer:Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
Reconstitution:Reconstitute with deionized water
Sequence:P53 (Met1-Asp393)+hFc(GLU99-ALA330)
Gene ID:
Uniprot:P04637
Molecular Weight:68.75 kDa
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