Human PI16 Recombinant Protein (RPPB2112)
- SKU:
- RPPB2112
- Product Type:
- Recombinant Protein
- Species:
- Human
- Uniprot:
- Q6UXB8
- Research Area:
- Enzymes
Frequently bought together:
Description
| Product Name: | Human PI16 Recombinant Protein |
| Product Code: | RPPB2112 |
| Size: | 10µg |
| Species: | Human |
| Target: | PI16 |
| Synonyms: | Peptidase inhibitor 16, PI-16, Cysteine-rich secretory protein 9, CRISP-9, PSP94-binding protein, PI16, CRISP9, PSPBP, MSMBBP, MGC45378, DKFZp586B1817. |
| Source: | HEK293 Cells |
| Physical Appearance: | Filtered White lyophilized (freeze-dried) powder. |
| Formulation: | PI16 was filtered (0.4�m) and lyophilized from 0.5mg/ml in 20mM Tris and 50mM NaCl, pH 7.5. |
| Solubility: | It is recommended to add deionized water to prepare a working stock solution of 0.5mg/ml and let the lyophilized pellet dissolve completely. Product is not sterile! Please filter the product by an appropriate sterile filter before using it in the cell culture. |
| Stability: | Store lyophilized PI16 Human recombinant at -20°C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted protein can be stored at 4°C for a limited period of time; it does not show any change after two weeks at 4°C. |
| Purity: | Greater than 95.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | LTDEEKRLMV ELHNLYRAQV SPPASDMLHM RWDEELAAFA KAYARQCVWG HNKERGRRGE NLFAITDEGM DVPLAMEEWH HEREHYNLSA ATCSPGQMCG HYTQVVWAKT ERIGCGSHFC EKLQGVEETN IELLVCNYEP PGNVKGKRPY QEGTPCSQCP SGYHCKNSLC EPIGSPEDAQ DLPYLVTEAP SFRATEASDS RKMGTPSSLA TGIPAFLVTE VSGSLATKAL PAVETQAPTS LATKDPPSMA TEAPPCVTTE VPSILAAHSL PSLDEEPVTF PKSTHVPIPK SADKVTDKTK VPSRSPENSL DPKMSLTGAR ELLPHAQEEA EAEAELPPSS EVLASVFPAQ DKPGELQATL DHTGHTSSKS LPNFPNTSAT ANATGGRALA LQSSLPGAEG PDKPSVVSGL NSGPGAAADY KDDDDK |
Peptidase Inhibitor 16 (PI16) which a member of the CRISP family, is a putative serine protease inhibitor. PI16 interacts with PSP94/MSMB. PI16 is expressed in the prostate, testis, ovary and intestine. It also concentrates in prostate cancer patient's sera. PI16 may serve as a marker following prostatectomy for prostate cancer.
The Peptidase Inhibitor 16 Human Recombinant is produced in HEK293 cells and fused with a C-terminal Flag Tag (11 amino acids). The PI16 Flag Tagged Fusion Protein is 45.7kDa protein containing a total of 426 amino acid residues and purified by proprietary chromatographic techniques.
| UniProt Protein Function: | PI16: Putative serine protease inhibitor. Belongs to the CRISP family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Membrane protein, integralChromosomal Location of Human Ortholog: 6p21.2 |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q6UXB8 |
| NCBI GenInfo Identifier: | 74749419 |
| NCBI Gene ID: | 221476 |
| NCBI Accession: | Q6UXB8.1 |
| UniProt Secondary Accession: | Q6UXB8,Q6ZVG9, Q8IYL8, Q8NBK0, Q8TCB8 |
| UniProt Related Accession: | Q6UXB8 |
| Molecular Weight: | 29,674 Da |
| NCBI Full Name: | Peptidase inhibitor 16 |
| NCBI Synonym Full Names: | peptidase inhibitor 16 |
| NCBI Official Symbol: | PI16�� |
| NCBI Official Synonym Symbols: | CD364; PSPBP; CRISP9; MSMBBP�� |
| NCBI Protein Information: | peptidase inhibitor 16 |
| UniProt Protein Name: | Peptidase inhibitor 16 |
| UniProt Synonym Protein Names: | Cysteine-rich secretory protein 9; CRISP-9; PSP94-binding protein |
| Protein Family: | Peptidase inhibitor |
| UniProt Gene Name: | PI16�� |
| UniProt Entry Name: | PI16_HUMAN |
