Human RNASE7 Recombinant Protein (RPPB2250)
- SKU:
- RPPB2250
- Product Type:
- Recombinant Protein
- Species:
- Human
- Uniprot:
- Q9H1E1
- Research Area:
- Enzymes
Frequently bought together:
Description
| Product Name: | Human RNASE7 Recombinant Protein |
| Product Code: | RPPB2250 |
| Size: | 10µg |
| Species: | Human |
| Target: | RNASE7 |
| Synonyms: | Ribonuclease, RNase A Family, 7, Skin-DerivedAntimicrobial Protein 2, RNase 7, SAP-2, EC 3.1.27.5, EC 3.1.27., EC 3.1.27, Ribonuclease 7. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered colorless solution. |
| Formulation: | RNASE7 protein solution (0.5mg/ml) containing 20mMTris-HCl buffer (pH8.0) and 10% glycerol 1mM DTT. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks.�Store, frozen at -20°C for longer periods of time.�For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 90% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHHSSGLVPRGSH MGSKPKGMTS SQWFKIQHMQ PSPQACNSAM KNINKHTKRC KDLNTFLHEPFSSVAATCQT PKIACKNGDK NCHQSHGPVS LTMCKLTSGK YPNCRYKEKR QNKSYVVACK PPQKKDSQQFHLVPVHLDRV L |
Ribonuclease 7 (RNASE7) is one of the final RNase A superfamily ribonucleases. RNASE7 was isolated from skin-derived stratum corneum. RNASE7 protein demonstrated potent ribonuclease activity and hence may contribute to the well-known ribonuclease activity of human skin. RNASE7 has revealed a broad spectrum antimicrobial activity against many pathogenic microorganisms and extraordinarily potent activity.
RNASE7 Human Recombinant produced in E.Coli is a single,non-glycosylated polypeptide chain containing 151 amino acids (29-156 a.a) andhaving a molecular mass of 16.9kDa.RNASE7 is fused to a 23amino acid His-tag at N-terminus & purified by proprietary chromatographictechniques.
| UniProt Protein Function: | Exhibits a potent RNase activity. Has broad-spectrum antimicrobial activity against many pathogenic microorganisms and remarkably potent activity (lethal dose of 90% < 30 nM) against a vancomycin resistant Enterococcus faecium. |
| NCBI Summary: | The protein encoded by this gene belongs to the pancreatic ribonuclease family, a subset of the ribonuclease A superfamily. The protein has broad-spectrum antimicrobial activity against bacteria and fungi. [provided by RefSeq, Oct 2014] |
| UniProt Code: | Q9H1E1 |
| NCBI GenInfo Identifier: | 14211885 |
| NCBI Gene ID: | 84659 |
| NCBI Accession: | NP_115961.1 |
| UniProt Secondary Accession: | Q9H1E1,P80927, P83685, Q546N3, |
| UniProt Related Accession: | Q9H1E1 |
| Molecular Weight: | 16.9 kDa (151aa) confirmed by MALDI-TOF |
| NCBI Full Name: | ribonuclease, RNase A family, 7 |
| NCBI Synonym Full Names: | ribonuclease A family member 7 |
| NCBI Official Symbol: | RNASE7�� |
| NCBI Official Synonym Symbols: | RAE1�� |
| NCBI Protein Information: | ribonuclease 7 |
| UniProt Protein Name: | Ribonuclease 7 |
| UniProt Synonym Protein Names: | Skin-derived antimicrobial protein 2; SAP-2 |
| Protein Family: | Ribonuclease |
| UniProt Gene Name: | RNASE7�� |
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