Description
| Product Name: | Human S100Z Recombinant Protein |
| Product Code: | RPPB4579 |
| Size: | 25µg |
| Species: | Human |
| Target: | S100Z |
| Synonyms: | Protein S100-Z, S100 calcium-binding protein Z, S100Z, Gm625, S100-zeta. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile filtered colorless solution. |
| Formulation: | S100Z Human solution (1mg/ml) containing 20mM Tris-HCl pH-8, 1mM DTT, 1mM EDTA, 50mM NaCl & 20% glycerol. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 95.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MPTQLEMAMD TMIRIFHRYS GKERKRFKLS KGELKLLLQR ELTEFLSCQK ETQLVDKIVQ DLDANKDNEV DFNEFVVMVA ALTVACNDYF VEQLKKKGK |
S100Z is a recently discovered member of the S100 protein family. S100 proteins are small dimeric members of the EF-hand superfamily of Ca(2+) binding proteins thought to participate in mediating intracellular Ca(2+) signals by binding to and thereby regulating target proteins in a Ca(2+)-dependent manner.S100Z is a 99-amino acid protein capable of interacting with another member of the family, S100P.There are differences in the expression level of S100Z mRNA in various tissues. The highest levels were found in spleen and leukocytes. S100Z gene expression appears to be deregulated in some tumor tissues, compared to expression in their normal counterparts.
S100Z Recombinant Human produced in E.Coli is a single, non-glycosylated polypeptide chain containing 119 amino acids (1-99 a.a.) and having a molecular mass of 13.7kDa. The S100Z is fused to a 20 amino acid His-Tag at N-terminus and purified by proprietary chromatographic techniques.
| UniProt Protein Function: | MiscellaneousThis protein binds two calcium ions. |
| UniProt Protein Details: | |
| NCBI Summary: | Members of the S100 protein family contain 2 calcium-binding EF-hands and exhibit cell-type specific expression patterns. For additional background information on S100 proteins, see MIM 114085.[supplied by OMIM, Mar 2008] |
| UniProt Code: | Q8WXG8 |
| NCBI GenInfo Identifier: | 150010678 |
| NCBI Gene ID: | 170591 |
| NCBI Accession: | NP_570128.2 |
| UniProt Secondary Accession: | Q8WXG8 |
| UniProt Related Accession: | Q8WXG8 |
| Molecular Weight: | 11 kDa |
| NCBI Full Name: | protein S100-Z |
| NCBI Synonym Full Names: | S100 calcium binding protein Z |
| NCBI Official Symbol: | S100Z�� |
| NCBI Official Synonym Symbols: | Gm625; S100-zeta�� |
| NCBI Protein Information: | protein S100-Z |
| UniProt Protein Name: | Protein S100-Z |
| UniProt Synonym Protein Names: | S100 calcium-binding protein Z |
| Protein Family: | Protein |
| UniProt Gene Name: | S100Z�� |
| UniProt Entry Name: |
