Human TGFBR1 Recombinant Protein (hFc Tag) (HDPT0120)
- SKU:
- HDPT0120
- Product Type:
- Recombinant Protein
- Species:
- Human
- Research Area:
- Immune Checkpoint
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Description
Human TGFBR1 Recombinant Protein (hFc Tag)
Description: | The protein encoded by this gene forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. The encoded protein is a serine/threonine protein kinase. Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS). Multiple transcript variants encoding different isoforms have been found for this gene. |
Product name: | Human TGFBR1 Recombinant Protein (hFc Tag) |
Synonyms: | AAT5; ACVRLK4; ALK-5; ALK5; ESS1; LDS1; LDS1A; LDS2A; MSSE; SKR4; tbetaR-I; TBR-i; TBRI; TGFR-1 |
Type: | protein |
Size: | 50 µg |
Name: | TGFBR1 |
Origin: | Human |
Source: | HEK293 |
Protein Type: | Recombinant |
Application: | Contact Technical Support |
Purity: | > 95% |
Purification: | affinity purification |
Format: | Lyophilized |
Conjugate: | N-Human Fc tag |
Storage: | Store at -80°C for 12 months (Avoid repeated freezing and thawing) |
Usage: | Research use only |
Buffer: | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization. |
Reconstitution: | Reconstitute with deionized water |
Sequence: | hFc(Glu99-Ala330)+TGFBR1(Leu34-Leu126) |
Gene ID: | 7046 |
Uniprot: | P36897 |
Molecular Weight: | 40-53 kDa |