Human TGFBR2 Recombinant Protein (hFc Tag) (HDPT0410)

SKU:
HDPT0410
Product Type:
Recombinant Protein
Host Species:
HEK293
Reactivity:
Human
€550

Description

Human TGFBR2 Recombinant Protein (hFc Tag)

Description:The protein encoded by this gene is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with TGF-beta receptor type-1, and binds TGF-beta. This receptor/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of genes related to cell proliferation, cell cycle arrest, wound healing, immunosuppression, and tumorigenesis. Mutations in this gene have been associated with Marfan Syndrome, Loeys-Deitz Aortic Aneurysm Syndrome, and the development of various types of tumors. Alternatively spliced transcript variants encoding different isoforms have been characterized. [provided by RefSeq, Aug 2017]
Product name:Human TGFBR2 Recombinant Protein (hFc Tag)
Synonyms:AAT3; FAA3; LDS1B; LDS2; LDS2B; MFS2; RIIC; TAAD2; TBR-ii; TBRII; TGFbeta-RII; TGFR-2
Type:protein
Size:50 µg
Name:TGFBR2
Origin:Human
Source:HEK293
Protein Type:Recombinant
Application:Contact Technical Support
Purity:Contact Technical Support
Purification:affinity purification
Format:Lyophilized
Conjugate:C-Human Fc
Storage:Store at -80°C for 12 months (Avoid repeated freezing and thawing)
Usage:Research use only
Buffer:Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
Reconstitution:Reconstitute with deionized water
Sequence:TGFBR2 (Thr23-Gln166)+hFc (Glu99-Ala330)
Gene ID:
Uniprot:P37173
Molecular Weight:41.36 kDa
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